Comparison of the feasibility of 3D printing technology in the treatment of pelvic fractures: a systematic review and me

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REVIEW ARTICLE

Comparison of the feasibility of 3D printing technology in the treatment of pelvic fractures: a systematic review and meta‑analysis of randomized controlled trials and prospective comparative studies Jinwu Wang1 · Xingyu Wang1 · Bingzhang Wang1 · Linzhen Xie1 · Wenhao Zheng1 · Hua Chen1 · Leyi Cai1 Received: 15 May 2020 / Accepted: 17 October 2020 © Springer-Verlag GmbH Germany, part of Springer Nature 2020

Abstract Purpose  The objective of this meta-analysis was to assess the influence of 3D printing technology on the open reduction and internal fixation (ORIF) of pelvic fractures from current randomized controlled trials and prospective comparative studies. Methods  In this meta-analysis, we conducted electronic searches of Pubmed, Embase, Cochrane library, Web of Science and CNKI up to February 2020. We collected clinical controlled trials using 3D printing-assisted surgery and traditional techniques to assist in pelvic fractures, evaluating the quality of the included studies and extracting data. The data of operation time, blood loss, follow-up function (Majeed function score), quality of fracture reduction (Matta score) and complications (infection, screw loosening, pelvic instability, venous thromboembolism, sacral nerve injury) were extracted. Stata 12.0 software was used for our meta-analysis. Results  Five RCTs and 2 prospective comparative studies met our inclusion criteria with 174 patients in the 3D printing group and 174 patients in the conventional group. There were significant differences in operation time [SMD = − 2.03], intraoperative blood loss [SMD = − 1.66] and postoperative complications [RR = 0.17] between the 3D group and conventional group. And the excellent and good rate of pelvic fracture reduction in the 3D group [RR = 1.32], the excellent and good rate of pelvic function [RR = 1.29] was superior to the conventional group. Conclusions  The 3D group showed shorter operation time, less intraoperative blood loss, less complications, better quality of fracture reduction and fast function recovery. Therefore, compared with conventional ORIF, ORIF assisted by 3D printing technology should be a more appropriate treatment of pelvic fractures. Keywords  Pelvic fractures · Three-dimensional printing · ORIF · Meta-analysis

Introduction Pelvic fractures were generally the result of high-energy trauma such as fall from height and motor vehicle accidents, accounting for about 3—8% of all fractures in human body [1, 2]. In addition, pelvic fractures were accompanied Jinwu Wang, Xingyu Wang, and Bingzhang Wang contributed equally to this work and should be considered as co-first authors. Hua Chen and Leyi Cai contributed equally to this work and should be considered as co-corresponding authors. * Leyi Cai [email protected]

by hemorrhagic shock, retroperitoneal hematoma, urethral injury and other multiple injuries, with a mortality rate of 50% and 60% [3]. Therefore, effective and timely management of pelvic fractures was very important. Clinically, the goals of pelvic fractures’ tre