Contact Urticaria Syndrome Diagnosis and Management

Contact urticaria is an immediate but transient localized swelling and redness that occurs on the skin after direct contact with an offending substance. It is caused by a variety of compounds, such as foods, preservatives, fragrances, plant and animal pro

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Ana M. Giménez-Arnau Howard I. Maibach Editors

Contact Urticaria Syndrome Diagnosis and Management

Updates in Clinical Dermatology Series Editors: John Berth-Jones Chee Leok Goh Howard I. Maibach

More information about this series at http://www.springer.com/series/13203

Ana M. Giménez-Arnau Howard I. Maibach Editors

Contact Urticaria Syndrome Diagnosis and Management

Editors Ana M. Giménez-Arnau, PhD Hospital del Mar - Institut Mar d’Investigacions Mediques Universitat Autònoma de Barcelona (UAB) Department of Dermatology Barcelona, Spain

Howard I. Maibach, MD Department of Dermatology University of California San Francisco San Francisco, CA, USA

ISSN 2523-8884     ISSN 2523-8892 (electronic) Updates in Clinical Dermatology ISBN 978-3-319-89763-9    ISBN 978-3-319-89764-6 (eBook) https://doi.org/10.1007/978-3-319-89764-6 Library of Congress Control Number: 2018946545 © Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Printed on acid-free paper This Springer imprint is published by the registered company Springer International Publishing AG part of Springer Nature. The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

I dedicate this book to my family, colleagues and patients – who give me confidence in my daily work. Ana M. Giménez-Arnau

Preface

We, as subjects who live in this world, are constantly exposed to environmental agents capable of stimulating our innate and acquired immunity. Our skin, as a complete immunological organ, recognizes such environmental agents and develops a mechanism of protection. But why does our cutaneous immune system sometimes recognize common environmental agents as foreign and develop active diseases such as eczema or urticaria? Are allergies a sign of a weak immune system? Signs and symptoms of the contact urticaria syndrome a