Endocarditis Diagnosis and Management
This timely new edition provides an up-to-date approach to the diagnosis and management of endocarditis. Each chapter from the previous edition has been updated to deliver a critical analysis on information gathered from the most recent studies on the sub
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Endocarditis Diagnosis and Management Second Edition
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Endocarditis
Kwan-Leung Chan • John M. Embil Editors
Endocarditis Diagnosis and Management Second Edition
Editors Kwan-Leung Chan Heart Institute University of Ottawa Ottawa, Ontario Canada
John M. Embil Department of Medicine Health Sciences Centre Winnipeg, Manitoba Canada
ISBN 978-3-319-27782-0 ISBN 978-3-319-27784-4 DOI 10.1007/978-3-319-27784-4
(eBook)
Library of Congress Control Number: 2016933665 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www. springer.com)
Foreword (1st Edition)
Infection remains the number one killer worldwide. Nevertheless, it is the expectation that bacterial infections can be eliminated with antibiotics. Unfortunately, there remain infections due to bacteria that are difficult to detect and difficult to reach, because of minimal blood supply, with even the most potent antibiotics. One of the diseases in this category is infections that initiate on the inner lining of a vital organ, the heart. These infections are referred to as endocarditis since they involve the endocardium, the inner lining of the heart and valves. The initial site of infection is generally in areas exposed to mechanical trauma or prosthetic device. Unfortunately the damage to the heart if not treated can be fatal and often survival requires surgical replacement of one of the valves. Despite the tremendous array of antibiotics and the marked increase in potency of these drugs to eradicate bacterial infection, the efficacy of treating the relatively avascular lining of the heart or its valvular apparatus often eludes the desired effect. This is further complicated by the changing substrate for bacterial endocarditis, namely, artificial valves and devices and the increasing number of individuals
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