Coronary artery stenosis-related perfusion ratio using dynamic computed tomography myocardial perfusion imaging: a pilot
- PDF / 1,053,476 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 84 Downloads / 224 Views
ORIGINAL ARTICLE
Coronary artery stenosis‑related perfusion ratio using dynamic computed tomography myocardial perfusion imaging: a pilot for identification of hemodynamically significant coronary artery disease Natsumi Kuwahara1 · Yuki Tanabe1 · Teruhito Kido1 · Akira Kurata1 · Teruyoshi Uetani2 · Hitomi Ochi1 · Naoto Kawaguchi1 · Tomoyuki Kido1 · Shuntaro Ikeda2 · Osamu Yamaguchi2 · Migiwa Asano3 · Teruhito Mochizuki1 Received: 26 May 2019 / Accepted: 14 October 2019 © The Author(s) 2019
Abstract The purpose of this study was to evaluate the feasibility of the stenosis-related quantitative perfusion ratio (QPR) for detecting hemodynamically significant coronary artery disease (CAD). Twenty-seven patients were retrospectively enrolled. All patients underwent dynamic myocardial computed tomography perfusion (CTP) and coronary computed tomography angiography (CTA) before invasive coronary angiography (ICA) measuring the fractional flow reserve (FFR). Coronary lesions with FFR ≤ 0.8 were defined as hemodynamically significant CAD. The myocardial blood flow (MBF) was calculated using dynamic CTP data, and CT-QPR was calculated as the CT-MBF relative to the reference CT-MBF. The stenosis-related CT-MBF and QPR were calculated using Voronoi diagram-based myocardial segmentation from coronary CTA data. The relationships between FFR and stenosis-related CT-MBF or QPR and the diagnostic performance of the stenosis-related CT-MBF and QPR were evaluated. Of 81 vessels, FFR was measured in 39 vessels, and 20 vessels (51%) in 15 patients were diagnosed as hemodynamically significant CAD. The stenosis-related CT-QPR showed better correlation (r = 0.70, p
Data Loading...
