Coronary Heart Disease Clinical, Pathological, Imaging, and Molecula

Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles presents a comprehensive picture of ischemic heart disease for practitioners, students, and investigators dealing with the varied facets of this complex subject.  Individ

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Zeev Vlodaver



Robert F. Wilson



Daniel J. Garry

Editors

Coronary Heart Disease Clinical, Pathological, Imaging, and Molecular Profiles

Editors Zeev Vlodaver Division of Cardiovascular Medicine University of Minnesota Minneapolis, MN, USA [email protected]

Robert F. Wilson Division of Cardiovascular Medicine University of Minnesota Minneapolis, MN, USA [email protected]

Daniel J. Garry Division of Cardiovascular Medicine University of Minnesota Minneapolis, MN, USA [email protected]

ISBN 978-1-4614-1474-2 e-ISBN 978-1-4614-1475-9 DOI 10.1007/978-1-4614-1475-9 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011943085 © Springer Science+Business Media, LLC 2012 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

This book is dedicated to our wives Dalia P. Vlodaver Betsy Wilson Mary G. Garry For their encouragement, devotion and support.

Preface

Coronary Heart Disease Clinical, Pathological, Imaging, and Molecular Profiles This book will present a comprehensive picture of ischemic heart disease to those who, either as practitioners, students or investigators, deal with the varied facets of this complex subject. It has meaning to the fields of clinical cardiology, thoracic surgery, pathology, and cardiovascular molecular research. After introductory chapters on the anatomy of the coronary blood vessels and cardiac development, several chapters will consider stress echo and nuclear diagnostics tests, noninvasive imaging and coronary angiography in ischemic heart disease, with techniques, indications, and examples of normal and abnormal patterns. In most instances, angiograms are paired with labeled line drawings, which help the initiated in the reading of films. Specific chapters will deal with congenital anomalies of the coronary arteries, which may engender states of ischemic heart disease. The principal thrust of the work concerns the main arena of ischemic h