COVID-19 and the brain: impact on nuclear medicine in neurology

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EDITORIAL

COVID-19 and the brain: impact on nuclear medicine in neurology Silvia Morbelli 1,2 & Ozgul Ekmekcioglu 3 & Henryk Barthel 4 & Nathalie L. Albert 5 & Ronald Boellaard 6 & Diego Cecchin 7 & Eric Guedj 8 & Adriaan A. Lammertsma 6 & Ian Law 9 & Ivan Penuelas 10 & Franck Semah 11 & Tatjana Traub-Weidinger 12 & Elsmarieke van de Giessen 13 & Andrea Varrone 14 & Valentina Garibotto 15,16 & EANM Neuroimaging Committee

# Springer-Verlag GmbH Germany, part of Springer Nature 2020

Introduction On 11 March 2020, the World Health Organization (WHO) declared the outbreak of coronavirus disease 2019 (COVID19) to be a pandemic [1]. The wide spread of infections led to an immediate urgency with the number of affected patients exceeding capacities of many involved healthcare systems with substantial morbidity and mortality [2]. During the pandemic emergency, hospitals and healthcare facilities all over the world were forced to postpone elective procedures. Thankfully, in keeping with different stages and timeframe of the curve of infection, it has been possible to progressively restart these activities over time in several countries [3]. Both during the pandemic crisis and in the present

transition phase, measures and precautions have been particularly relevant for fragile patients [3, 4]. In fact, comorbidities together with age have been demonstrated as important prognostic factors for the severity of disease in patients affected by SARS-CoV-2 [2, 5]. Among fragile subjects, patients with chronic neurological disease are more susceptible to the effects of the infection, particularly involving the respiratory tract [6, 7]. Impairment of central respiratory centres (CNS) could also contribute to the severe acute respiratory syndrome associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [8]. Given the high impact of these disorders on human health, there is a present need to progressively restore necessary access and care for patients affected by neurological and

This article is part of the Topical Collection on Infection and Inflammation * Silvia Morbelli [email protected] 1

IRCCS Ospedale Policlinico San Martino, Genoa, Italy

2

Nuclear Medicine Unit, IRCCS Ospedale Policlinico San Martino, Department of Health Sciences(DISSAL), University of Genoa, Genoa, Italy

3

Department of Nuclear Medicine, Sisli Etfal Education and Research Hospital, Istanbul, Turkey

4

Department of Nuclear Medicine, Leipzig University, Leipzig, Germany

5

Department of Nuclear Medicine, Ludwig Maximilians-University of Munich, Munich, Germany

6

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, De Boelelaan, 1117 Amsterdam, Netherlands

7

Nuclear Medicine Unit, Department of Medicine – DIMED, University of Padua, Padua, Italy

8

APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Nuclear Medicine Department, Aix Marseille Univ, Marseille, France

9

Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, University of Co