Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient

This volume provides a comprehensive overview of critical care of the pediatric immunocompromised hematology-oncology patient. The text focuses on unique aspects of the pediatric immunocompromised patient that predisposes the child to significant illness,

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Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient

Christine N. Duncan Julie-An M. Talano  •  Jennifer A. McArthur Editors

Critical Care of the Pediatric Immunocompromised Hematology/Oncology Patient An Evidence-Based Guide

Editors Christine N. Duncan Pediatric Hematology-Oncology Dana-Farber Cancer Institute Boston, MA USA Jennifer A. McArthur Department of Pediatric Medicine St. Jude Children’s Research Hospital Memphis, TN USA

Julie-An M. Talano Children’s Hospital of Wisconsin-Milwaukee Medical College of Wisconsin Milwaukee, WI USA

ISBN 978-3-030-01321-9    ISBN 978-3-030-01322-6 (eBook) https://doi.org/10.1007/978-3-030-01322-6 Library of Congress Control Number: 2018965743 © Springer International Publishing 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

To families of children with cancer and hematological disorders that we have cared for in our ICUs

Contents

Part I Predisposing Diseases and Specific Considerations in Critical Illness 1 The Changing Landscape of the Critical Care of Pediatric Immunocompromised Hematology and Oncology Patients ������������������   3 Christine N. Duncan 2 Diagnosis and Treatment-Related Complications of Acute Leukemia ����������������������������������������������������������������������������������������   9 Lauren Pommert, Steven Margossian, and Michael Burke 3 Neuro-oncologic Emergencies  ������������������������������������������������������������������  29 Jessica Clymer and Peter E. Manley 4 Solid Tumors Outside of the Central Nervous System ��������������������������  41 Hilary C. Schreiber and James S. Killinger 5 Primary Immunodeficiency Diseases  ����������������������������������������