Cytopathology of Infectious Diseases

The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each vo

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ESSENTIALS IN CYTOPATHOLOGY Dorothy L. Rosenthal, MD, FIAC, Series Editor Editorial Board

Syed Z. Ali, MD Douglas P. Clark, MD Yener S. Erozan, MD

For further volumes: http://www.springer.com/series/6996

Liron Pantanowitz, MD, MIAC Pam Michelow, MBBCh, MSc (Med Sci) Walid E. Khalbuss, MD, PhD, FIAC

Cytopathology of Infectious Diseases Including Chapters 2 & 14 Co-authored by: Tanvier Omar, MB BCH, FC Path (S.A.) Chapters 3, 9, 10 & 13 Co-authored by: Sara E. Monaco, MD Chapter 4 Co-authored by: Gladwyn Leiman, MBBCh, FIAC, FRCPath Lynne S. Garcia, MS, CLS, FAAM Chapter 5 Co-authored by: R. Marshall Austin, MD, PhD Chapter 6 Co-authored by: Rodolfo Laucirica, MD Chapter 7 Co-authored by: Robert M. Najarian, MD Helen H. Wang, MD, PhD Chapter 8 Co-authored by: Anil V. Parwani, MD, PhD and Chapter 15 Co-authored by: Robert A. Goulart, MD Rafael Martínez-Girón, MD, PhD

Liron Pantanowitz, MD, MIAC Department of Pathology University of Pittsburgh Medical Center Pittsburgh, PA 15232, USA [email protected] Walid E. Khalbuss, MD, PhD, FIAC Department of Pathology University of Pittsburgh Medical Center Pittsburgh, PA 15232, USA [email protected]

Pam Michelow, MBBCh, MSc (Med Sci) Department of Anatomical Pathology, University of the Witwatersrand & National Health Laboratory Service Johannesburg 2000, South Africa [email protected]

ISSN 1574-9053 e-ISSN 1574-9061 ISBN 978-1-4614-0241-1 e-ISBN 978-1-4614-0242-8 DOI 10.1007/978-1-4614-0242-8 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2011932800 © Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

This book is dedicated to my wife Heidi and children Joshua and Maya. Liron Pantanowitz, MD, MIAC To my husband Alan and children Gina, Matt, and Aaron. Pam Michelow, MBBCh, MSc (Med Sci) To my family, mentors, trainees, and friends for their encouragement and support. Walid