Data Integration in the Life Sciences 5th International Workshop, DI
This book constitutes the refereed proceedings of the 5th International Workshop on Data Integration in the Life Sciences, DILS 2008, held in Evry, France in June 2008. The 18 revised full papers presented together with 3 keynote talks and a tutorial pape
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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong
Subseries of Lecture Notes in Computer Science
Amos Bairoch Sarah Cohen-Boulakia Christine Froidevaux (Eds.)
Data Integration in the Life Sciences 5th International Workshop, DILS 2008 Evry, France, June 25-27, 2008 Proceedings
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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editors Amos Bairoch University of Geneva, Swiss Institute of Bioinformatics and Department of Structural Biology and Bioinformatics CMU – 1, rue Michel Servet, 1211 Geneva 4, Switzerland E-mail: [email protected] Sarah Cohen-Boulakia Christine Froidevaux Université Paris-Sud 11, Laboratoire de Recherche en Informatique Bâtiment 490, 91405 Orsay Cedex, France E-mail: {cohen, chris}@lri.fr
Library of Congress Control Number: Applied for
CR Subject Classification (1998): H.2, H.3, H.4, J.3 LNCS Sublibrary: SL 8 – Bioinformatics ISSN ISBN-10 ISBN-13
0302-9743 3-540-69827-2 Springer Berlin Heidelberg New York 978-3-540-69827-2 Springer Berlin Heidelberg New York
This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com © Springer-Verlag Berlin Heidelberg 2008 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper SPIN: 12282746 06/3180 543210
Preface
For several years now, there has been an exponential growth of the amount of life science data (e.g., sequenced complete genomes, 3D structures, DNA chips, mass spectroscopy data), most of which are generated by high-throughput experiments. This exponential corpus of data is stored and made available through a large number of databases and resources over the Web, but unfortunately still with a high degree of semantic heterogeneity and varying levels of quality. These data must be combined together and processed by bioinformatics tools deployed on powerful and efficient platforms to permit the uncovering of patterns, similarities and in general to help in the process of discovery. Analyzing complex, voluminous, and heterogeneous data and guiding the analysis of data are thus of paramount importance and necessitate the involvement of data integration te
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