Data Mining and Bioinformatics First International Workshop, VDMB 20

This volume contains the papers presented at the inaugural workshop on Data Mining and Bioinformatics at the 32nd International Conference on Very Large Data Bases (VLDB). The purpose of this workshop was to begin bringing - gether researchersfrom databas

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Edited by S. Istrail, P. Pevzner, and M. Waterman Editorial Board: A. Apostolico S. Brunak M. Gelfand T. Lengauer S. Miyano G. Myers M.-F. Sagot D. Sankoff R. Shamir T. Speed M. Vingron W. Wong

Subseries of Lecture Notes in Computer Science

Mehmet M. Dalkilic Sun Kim Jiong Yang (Eds.)

Data Mining and Bioinformatics First International Workshop, VDMB 2006 Seoul, Korea, September 11, 2006 Revised Selected Papers

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Series Editors Sorin Istrail, Brown University, Providence, RI, USA Pavel Pevzner, University of California, San Diego, CA, USA Michael Waterman, University of Southern California, Los Angeles, CA, USA Volume Editors Mehmet M. Dalkilic Sun Kim Indiana University Center for Genomics and Bioinformatics School of Informatics Bloomington,IN 47408, USA E-mail: {dalkilic,sunkim2}@indiana.edu Jiong Yang Case Western Reserve University EECS Department, Department of Epidemiology and Biostatistics Cleveland, OH, 44106, USA E-mail: [email protected]

Library of Congress Control Number: 2006938545

CR Subject Classification (1998): H.2.8, I.5, J.3, I.2, H.3, F.1-2 LNCS Sublibrary: SL 8 – Bioinformatics ISSN ISBN-10 ISBN-13

0302-9743 3-540-68970-2 Springer Berlin Heidelberg New York 978-3-540-68970-6 Springer Berlin Heidelberg New York

This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, re-use of illustrations, recitation, broadcasting, reproduction on microfilms or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permission for use must always be obtained from Springer. Violations are liable to prosecution under the German Copyright Law. Springer is a part of Springer Science+Business Media springer.com © Springer-Verlag Berlin Heidelberg 2006 Printed in Germany Typesetting: Camera-ready by author, data conversion by Scientific Publishing Services, Chennai, India Printed on acid-free paper SPIN: 11960669 06/3142 543210

Preface

This volume contains the papers presented at the inaugural workshop on Data Mining and Bioinformatics at the 32nd International Conference on Very Large Data Bases (VLDB). The purpose of this workshop was to begin bringing together researchers from database, data mining, and bioinformatics areas to help leverage respective successes in each to the others. We also hope to expose the richness, complexity, and challenges in this area that involves mining very large complex biological data that will only grow in size and complexity as genomescale high-throughput techniques become more routine. The problems are sufficiently different enough from traditional data mining problems (outside of life sciences) that novel approaches must be taken to data mine in this area. The workshop was held in Seoul, Korea, on September 11, 2006. We received 30 submissions in response to the call for papers. Each submission was assi