Dealing with the lack of evidence to treat depression in older patients with cancer: French Societies of Geriatric Oncol
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REVIEW ARTICLE
Dealing with the lack of evidence to treat depression in older patients with cancer: French Societies of Geriatric Oncology (SOFOG) and PsychoOncology (SFFPO) position paper based on a systematic review Bérengère Beauplet 1,2,3 & Ophélie Soulie 4 & Jean-Yves Niemier 5,6 & Cécile Pons-Peyneau 7 & Drifa Belhadi 8,9 & Camille Couffignal 8,9 & Virginie Fossey-Diaz 10,11 Received: 29 April 2020 / Accepted: 12 August 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Introduction Depression symptoms, frequently diagnosed in older patients with cancer, impacts on oncological treatment feasibility. The Francophone Society of Geriatric Oncology (SOFOG) has initiated a systematic review on depression treatment in older patients with cancer, to advocate guidelines. Data sources Medline via PubMed, Embase, CENTRAL. Methods We included randomized and non-randomized controlled trials, reviews and meta-analysis, retrospective and prospective cohort studies, qualitative studies, and guidelines published between January 2013 and December 2018 that involved depression with cancer in which the entire sample or a sub-group aged 65 and above. Efficacy and tolerance of depression treatment were examined, as a primary or secondary outcome, among articles published in French or English. Results Of 3171 references, only seven studies met our eligibility criteria. This systematic review reveals a lack of evidencebased knowledge in this field, preventing from making any recommendations on drug and non-drug therapies. It has highlighted the need for multidisciplinary collaboration with the French and Francophone Society of Psycho-Oncology. Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00520-020-05682-9) contains supplementary material, which is available to authorized users. * Bérengère Beauplet [email protected]
Department of Geriatric Medicine, Caen Universitary Hospital Center, Avenue Côte de Nacre, 14 033 cedex 9 Caen, France
3
Ophélie Soulie [email protected]
Normandie University, UniCaen, INSERM, U1086, ANTICIPE, Avenue du General Harris, 14000 Caen, France
4
Jean-Yves Niemier [email protected]
Psycho-Oncology Unit, Supportive Care Department, Curie Institute, 75005 Paris, France
5
Cécile Pons-Peyneau [email protected]
Department of Geriatric Oncology, Nancy University Hospital Center, 54511 Vandoeuvre-lès-Nancy, France
6
Lorraine Oncogeriatric Coordination Unit, 54511 Vandoeuvre-lès-Nancy, France
7
Camille Couffignal [email protected]
Department of Psychiatry, Chardon-Lagache Hospital, 75016 Paris, France
8
Biostatistics and Clinical Research Unit, AP-HP Northern Group, Bichat-Claude Bernard Hospital, Paris, France
Virginie Fossey-Diaz [email protected]
9
Paris University, INSERM, CIC-EC 1425, Bichat-Claude Bernard Hospital, Paris, France
10
Department of Geriatric Medicine and Palliative Care, Bretonneau Hospital Center, 75018 Paris, France
11
Oncogeriatric Coordination Unit, Pari
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