Defining critical factors in multi-country studies of assisted reproductive technologies (ART): data from the US and UK
- PDF / 323,293 Bytes
- 9 Pages / 595.276 x 790.866 pts Page_size
- 108 Downloads / 169 Views
ASSISTED REPRODUCTION TECHNOLOGIES
Defining critical factors in multi-country studies of assisted reproductive technologies (ART): data from the US and UK health systems Michael L. Eisenberg 1,2 & Barbara Luke 3 & Katherine Cameron 4 & Gary M. Shaw 5 & Allan A. Pacey 6 & Alastair G. Sutcliffe 7 & Carrie Williams 7 & Julian Gardiner 8 & Richard A. Anderson 9 & Valerie L. Baker 3 Received: 17 August 2020 / Accepted: 13 September 2020 # Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract As the worldwide use of assisted reproductive technologies (ART) continues to grow, there is a critical need to assess the safety of these treatment parameters and the potential adverse health effects of their use in adults and their offspring. While key elements remain similar across nations, geographic variations both in treatments and populations make generalizability challenging. We describe and compare the demographic factors between the USA and the UK related to ART use and discuss implications for research. The USA and the UK share some common elements of ART practice and in how data are collected regarding long-term outcomes. However, the monitoring of ART in these two countries each brings strengths that complement each other’s limitations. Keywords Fertilization in vitro . Infertility . Education . Social class
Introduction As the worldwide use of assisted reproductive technologies (ART) continues to grow, there is a critical need to assess the safety of these treatment parameters and the potential adverse health effects of their use in adults and their offspring [1, 2]. The challenge for this type of research is that the practice of fertility treatment is constantly evolving, such that the longterm health outcomes evaluated today reflect therapies that have long since been updated. While critical, it can be challenging to assemble datasets that reflect contemporary IVF
* Michael L. Eisenberg [email protected] 1
Division of Male Reproductive Medicine and Surgery, Department of Urology, Stanford University School of Medicine, Palo Alto, CA, USA
2
Department of Urology, Stanford University School of Medicine, 300 Pasteur Dr., Stanford, CA, USA
3
Department of Obstetrics, Gynecology, and Reproductive Biology, College of Human Medicine, Michigan State University, East Lansing, MI, USA
and ART therapies but that also encompass enough prior years to have mature outcomes as the recipients (and offspring) have aged. One of the lessons learned from the worldwide pandemic of 2019–2020 has been the strength in collaboration between countries, which allows for increased participants for studies, faster enrollment, shared intellect and knowledge, and improved generalizability of cohorts given inherent variations in practice patterns and patient response to disease and therapy. By forming international partnerships, we can apply these lessons to studies of ART to construct linked datasets with
4
Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns H
Data Loading...
