Desmopressin
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Desmopressin Neurological symptoms in the form of generalised tonic-clonic seizure and cerebral oedema secondary to hyponatraemia: 2 case reports
In a case series, two women (a pregnant woman who had Von Willebrand disease and another woman who had thrombocyte disfunction) [ages not stated] were described, who developed severe neurological symptoms in the form of generalised tonic-clonic seizure and cerebral oedema secondary to hyponatraemia following occasional use of desmopressin. Over 24 hours of use of desmopressin, both these women developed generalised tonic-clonic seizures and cerebral oedema secondary to serious hyponatraemia [dosages, routes and outcomes not stated]. Szigeti L, et al. Severe neurology symptoms after desmopressin administration. European Journal of Neurology 27 (Suppl. 1): 1007 (plus poster) abstr. EPO2389, May 2020. 803498559 Available from: URL: https://www.ean.org/fileadmin/user_upload/ean/congress-2020/Present/Abstracts/00_EAN_Journal_2020_Book.pdf [abstract]
0114-9954/20/1819-0001/$14.95 Adis © 2020 Springer Nature Switzerland AG. All rights reserved
Reactions 29 Aug 2020 No. 1819
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