Population Pharmacokinetics of Clotting Factor Concentrates and Desmopressin in Hemophilia
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REVIEW ARTICLE
Population Pharmacokinetics of Clotting Factor Concentrates and Desmopressin in Hemophilia Tim Preijers1 · Lisette M. Schütte2 · Marieke J. H. A. Kruip2 · Marjon H. Cnossen3 · Frank W. G. Leebeek2 · Reinier M. van Hest1 · Ron A. A. Mathôt1,4
© The Author(s) 2020
Abstract Hemophilia A and B are bleeding disorders caused by a deficiency of clotting factor VIII and IX, respectively. Patients with severe hemophilia (
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