Detection and clinical characteristics of serrated polyps and conventional adenomas between patients in the outpatient a
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ORIGINAL ARTICLE
Detection and clinical characteristics of serrated polyps and conventional adenomas between patients in the outpatient and physical checkup unit receiving colonoscopy Min-Chi Chang 1,2 & Chen-Chung Ma 3 & Hsien-Chung Yu 4 & Ping-I Hsu 5 & Jia-Bin Liao 6,7 & Chun-Che Huang 3 Accepted: 10 June 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose The sessile serrated adenoma/polyp detection rate (SSA/PDR) among different colonoscopy indications from daily practice has not been fully understood. This study aimed to evaluate the detection and clinical characteristics of serrated polyps and conventional adenomas between outpatient department (OPD) and physical checkup unit (PCU) patients receiving colonoscopy. Methods The data for this retrospective study were collected between 2016 and 2017 at Kaohsiung Veterans General Hospital in Taiwan. A total of 7047 individuals were included, and information on polyp and adenoma detection was extracted from the colonoscopy reports. Results The adenoma detection rate, the SSA/PDR, and the detection rate of traditional serrated adenoma (TSA) were 32.2%, 0.60%, and 0.50%, respectively. Risk analysis revealed no significant difference (p = 0.095) in SSA/PDR between individuals < 50 years and ≥ 50 years, and no trend of increased SSA/PDR as age increased was observed (p = 0.320). SSA/P and TSA had higher risks for synchronous advanced neoplasia than conventional adenoma, but with proximal hyperplastic polyps lower (p < 0.001, respectively). No significant difference of SSA/PDR between OPD and PCU patients was observed (p = 1.000); however, the age of SSA/P was significantly older in OPD than in PCU patients (p = 0.048). Conclusion The detection rates of CA and TSA were associated with age groups; however, SSA/PDR was insignificantly higher among individuals aged < 50 years than those with other age groups. In addition, SSA/PDR between OPD and PCU patients was not significantly found in daily practice of colonoscopies. Keywords Serrated polyps . Sessile serrated adenoma/polyp . Traditional serrated adenoma . Hyperplastic polyps
Introduction The incidence of colorectal and anal cancer has become the highest among the various cancers since 2008 in Taiwan, with
age-standardized incidence rate of 41.29 per 100,000 populations in 2016 [1]. In the pathways of malignant transformation of colorectal cancers (CRCs), the serrated pathway accounts for 30–35% of the total CRC malignant development [2, 3].
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s00384-020-03665-0) contains supplementary material, which is available to authorized users. * Jia-Bin Liao [email protected]
4
Health Management Center, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
* Chun-Che Huang [email protected]; [email protected]
5
Department of Medicine, Tainan Municipal An-Nan Hospital, China Medical University, Tainan, Taiwan
6
Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General
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