Diagnostic performance in gastric cancer is higher using endocytoscopy with narrow-band imaging than using magnifying en
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ORIGINAL ARTICLE
Diagnostic performance in gastric cancer is higher using endocytoscopy with narrow‑band imaging than using magnifying endoscopy with narrow‑band imaging Yusuke Horiuchi1 · Toshiaki Hirasawa1 · Naoki Ishizuka2 · Hiroyuki Hatamori1 · Yohei Ikenoyama1 · Junki Tokura1 · Mitsuaki Ishioka1 · Yoshitaka Tokai1 · Ken Namikawa1 · Shoichi Yoshimizu1 · Akiyoshi Ishiyama1 · Toshiyuki Yoshio1 · Tomohiro Tsuchida1 · Junko Fujisaki1 Received: 14 August 2020 / Accepted: 18 September 2020 © The International Gastric Cancer Association and The Japanese Gastric Cancer Association 2020
Abstract Background For diagnosing gastric cancer, differences in the diagnostic performance between endocytoscopy with narrowband imaging and magnifying endoscopy with narrow-band imaging have not been reported. We aimed to clarify these differences by analyzing diagnoses made by endoscopists in Japan. Methods This single-center retrospective cohort study used 106 cancerous and 106 non-cancerous images obtained via both modalities (total, 424 images) for diagnosis. Sixty-one endoscopists with varying experience levels from 45 institutions were included. Diagnostic accuracy, sensitivity, specificity, and positive and negative predictive values were evaluated to determine the diagnostic performance of each modality and compared using the Mann–Whitney U test. Results Among all endoscopists, diagnostic accuracy, sensitivity, positive predictive value, and negative predictive value were higher with endocytoscopy with narrow-band imaging than with magnifying endoscopy with narrow-band imaging (percentage [95% confidence interval]: 78.8% [76.4–83.0%] versus 72.2% [69.3–73.6%], p
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