Diazoxide
- PDF / 140,938 Bytes
- 1 Pages / 595.245 x 841.846 pts (A4) Page_size
- 71 Downloads / 153 Views
1
S
Pericardial effusion in a child: case report A 3-year-old boy developed pericardial effusion during treatment with diazoxide for congenital hyperinsulinism. He started oral diazoxide [Proglycem] 10 mg/kg/day. Within a month, he developed a large pericardial effusion, which required drainage. Diazoxide was switched to octreotide. Subsequently, diazoxide was restarted at 1 mg/kg/day, and increased to 4 mg/kg/day by 2 weeks. Minimal pericardial effusion was detected by weekly echocardiography. After diazoxide was withdrawn, his effusion resolved, and he underwent subtotal pancreatectomy. Author comment: "In this case report, we have observed pericardial effusion at both high and low doses of diazoxide in a child with a structurally normal heart." Avatapalle B, et al. Echocardiography monitoring for diazoxide induced pericardial effusion. BMJ Case Reports 2012: [1 page], 2012. Available from: URL: http:// 803077928 dx.doi.org/10.1136/bcr.03.2012.6110 - United Kingdom
0114-9954/10/1422-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Reactions 6 Oct 2012 No. 1422
