Disorders of Movement A Guide to Diagnosis and Treatment

The prevalence of all movement disorders among the general population has been estimated to be about 25%; they are thus among the most common neurological conditions. Although the past 25 years have witnessed outstanding growth in knowledge on the phenome

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Disorders of Movement A Guide to Diagnosis and Treatment

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Disorders of Movement

Davide Martino • Alberto J. Espay Alfonso Fasano • Francesca Morgante

Disorders of Movement A Guide to Diagnosis and Treatment

Davide Martino, MD, PhD Consultant Neurologist and Honorary Senior Lecturer Neurology Department King’s College Hospital NHS Foundation Trust London UK Alberto J. Espay, MD, MSc Associate Professor of Neurology James J. and Joan A. Gardner Center for Parkinson’s Disease and Movement Disorders, University of Cincinnati Cincinnati, Ohio USA

Alfonso Fasano, MD, PhD Associate Professor of Medicine Division of Neurology University of Toronto Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson’s Disease Toronto Western Hospital, UHN Toronto, Ontario Canada Francesca Morgante, MD, PhD Assistant Professor Neurology Department of Clinical and Experimental Medicine University of Messina Messina Italy

ISBN 978-3-662-48466-1 ISBN 978-3-662-48468-5 DOI 10.1007/978-3-662-48468-5

(eBook)

Library of Congress Control Number: 2015955471 Springer Heidelberg New York Dordrecht London © Springer-Verlag Berlin Heidelberg 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer-Verlag GmbH Berlin Heidelberg is part of Springer Science+Business Media (www.springer.com)

We are grateful to our patients and mentors for their invaluable lessons and to our families for patiently and supportively accepting that there is no end to medical learning. To Kristy Joy, humanity’s magnificent monument to womanhood A.J.E. To my beloved Father F.M. To Nusco and the many travel mates I met so far in this journey A.F. To Eva and Federico D.M.

Foreword

While the main symptoms of movement disorders are clearly defined, patients do not necessarily respect the arbitrary grouping of symptoms that have traditionally defined recognized diseases. Hence, it is refreshing to see a new text that starts with an agnostic view of the