Dosimetric evaluation of a rotating gamma-ray system for stereotactic body radiation therapy
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ORIGINAL RESEARCH
Dosimetric evaluation of a rotating gamma-ray system for stereotactic body radiation therapy Ahmed Eldib 1 & Muhammad Fareed 2 & Stephanie Weiss 1 & Shelly Hayes 1 & Binh Nguyen 3 & Grisel Mora 4 & Jinsheng Li 5 & Omar Chibani 1 & Mahmoud Abdelgawad 6 & C-M. Charlie Ma 1 Received: 24 January 2020 / Accepted: 11 October 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Purpose Gamma-ray stereotactic radiosurgery systems available commercially contain either stationary or rotational source configuration. Rotational systems reduce the number of sources utilized and can also provide beneficial dosimetric properties. In this study, we explore the dosimetric advantage of a novel rotating gamma-ray design for stereotactic body radiotherapy (SBRT) as compared to the well-established CyberKnife system. Materials and methods CybeRay (OUR United Corp., Xian, China) is a rotating gamma-ray system (RGS). Its treatment head can rotate 360° in the axial plane and swing 35° in the superior direction. It includes 13 Co-60 sources focusing on the isocenter. The RT Pro planning system (Prowess, Concord, CA) was used for CybeRay treatment planning, while the Multiplan software (Accuray, Sunnyvale, CA) was used for CyberKnife treatment planning. Twelve SBRT patients previously treated with CyberKnife were re-planned for CybeRay, and their treatment plans were compared based on isodose distributions, dose volume histograms, conformity index (CI), and the estimated treatment time. Results The planning target volume ranged from 4.4 to 124.2 cc. Both treatment systems provided excellent SBRT plans that meet our clinical acceptance criteria. The mean value of CI was 1.25 for both CyberKnife and CybeRay (p = 0.03). The estimated treatment delivery time for the CyberKnife plans ranged from 13 to 53 min as compared to 6 to 54 min with CybeRay (p = 0.02). CybeRay was superior concerning peripheral doses appearing as excessive isodose lines extending to distal normal tissues. Conclusion The new CybeRay machine showed promising dosimetric capabilities for stereotactic radiosurgery and radiotherapy of extra- and intra-cranial lesions. Keywords Gamma knife . Rotating gamma system . CybeRay . CyberKnife
Introduction * Ahmed Eldib [email protected] 1
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
2
Department of Radiation Oncology, Dana-Farber/Brigham & Women’s Cancer Center, Harvard Medical School, Boston, MA, USA
3
Prowess, Concord, CA, USA
4
Institute of Biophysics and Biomedical Engineering, Faculty of Sciences, University of Lisbon, Lisbon, Portugal
5
OUR United Corporation, Xian, China
6
Biophysics branch, Physics Department, Faculty of science, Al-Azhar University, Cairo, Egypt
Radiosurgery has become an important treatment alternative to surgery for a variety of intracranial lesions. Stereotactic radiosurgery/radiotherapy (SRS/SRT) delivered with the current state-of-the-art techniques has provided excellent target dose conformity, targeting precisi
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