Drug Treatment of Sleep Disorders

Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorde

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Antonio Guglietta Editor

Drug Treatment of Sleep Disorders

Milestones in Drug Therapy

Series Editors Michael J. Parnham, Fraunhofer IME & Goethe University Frankfurt, Germany Jacques Bruinvels, Bilthoven, The Netherlands Advisory Board J.C. Buckingham, Imperial College School of Medicine, London, UK R.J. Flower, The William Harvey Research Institute, London, UK A.G. Herman, Universiteit Antwerpen, Antwerp, Belgium P. Skolnick, National Institute on Drug Abuse, Bethesda, MD, USA

More information about this series at http://www.springer.com/series/4991

Antonio Guglietta Editor

Drug Treatment of Sleep Disorders

Editor Antonio Guglietta Independent Pharmaceutical Consultant Barcelona Spain

ISSN 2296-6056 ISSN 2296-6064 (electronic) ISBN 978-3-319-11513-9 ISBN 978-3-319-11514-6 (eBook) DOI 10.1007/978-3-319-11514-6 Springer Cham Heidelberg New York Dordrecht London Library of Congress Control Number: 2014957395 © Springer International Publishing Switzerland 2015 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher’s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Sleep disorders are very common in the modern society. In the United States it is calculated that between 50 and 70 million of people suffer from some kind of sleep disorder while it is estimated that in the developing countries across the wor