Ebola Virus Disease A Manual for EVD Management

This current manual gives an overview to management of Ebola Virus Disease outbreaks from a practical point of view. It gives an introduction to the topic, reviews the history and previous outbreaks of Ebola virus disease and gives insight to clinical fea

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Ebola Virus Disease A Manual for EVD Management

Ebola Virus Disease

Marta Lado Editor

Ebola Virus Disease A Manual for EVD Management

Editor Marta Lado King’s Sierra Leone Partnership Freetown, Sierra Leone

ISBN 978-3-319-94853-9 ISBN 978-3-319-94854-6 https://doi.org/10.1007/978-3-319-94854-6

(eBook)

Library of Congress Control Number: 2018965918 # Springer International Publishing AG, part of Springer Nature 2018 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Contents

1

Introduction to Viral Haemorrhagic Fevers . . . . . . . . . . . . . . . . . . . Colin S. Brown and Oliver Johnson

2

Clinical Features, Case Definition and Clinical Management of Ebola Virus Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marta Lado, Colin S. Brown, Naomi F. Walker, Daniel Youkee, Oliver Johnson, Andy Hall, Patrick Howlett, Hooi-Ling Harrison, Felicity Fitzgerald, and Natalie Mounter

1

9

3

Response to an EVD Outbreak . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Marta Lado, Natalie Mounter, Daniel Youkee, and Andy Hall

19

4

Ebola Virus Disease in the Obstetric Population . . . . . . . . . . . . . . . . Colin S. Brown, Diana Garde, Emily Headrick, Felicity Fitzgerald, Andy Hall, Hooi-Ling Harrison, and Naomi F. Walker

87

5

Diagnostics in Ebola Virus Disease . . . . . . . . . . . . . . . . . . . . . . . . . . 145 Colin S. Brown, Robert Shorten, and Naomi F. Walker

6

Sequelae of Ebola Virus Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 Patrick Howlett and Marta Lado

Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 189

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1

Introduction to Viral Haemorrhagic Fevers C