Effect of platelet-rich plasma on healing in laser pilonidoplasty for pilonidal sinus disease
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ORIGINAL ARTICLE
Effect of platelet-rich plasma on healing in laser pilonidoplasty for pilonidal sinus disease Feyzi Kurt 1 & Selim Sözen 2 & Burhan Hakan Kanat 3 & Nizamettin Kutluer 3 & Onur Sakalli 4 & Mehmet Gençtürk 5 & Zekiye Kanat 3 Received: 28 April 2020 / Accepted: 24 August 2020 # Springer-Verlag London Ltd., part of Springer Nature 2020
Abstract The aim of this study was to evaluate the effects of application of platelet-rich plasma in addition to laser pilonidoplasty for the treatment of pilonidal sinus. Twenty-five patients who were treated by laser pilonidoplasty for pilonidal sinus (group 1) and 25 patients who were treated by platelet-rich plasma in addition to laser pilonidoplasty (group 2) at this clinic were included in the study. Patients were classified according to the Irkorucu and Adana Numune’s classification and treatment concept. Duration of stay of the patients in the hospital, time to start daily activities, duration of wound healing, recurrence, and complications were evaluated. Among the 50 patients included in the study, 41 (%82) were males and 9 (%18) were females. The mean age was 25.6 ± 2.4 years and 24.8 ± 3.8 years in groups 1 and 2, respectively. The locations of the pilonidal sinus were similar in the two groups. No statistically significant differences were found in the duration of hospital stay, duration of the procedure, time to return to work, and complication rates between the two groups. Nevertheless, duration of wound healing was 6.1 ± 2.3 and 4.1 ± 0.9 weeks in groups 1 and 2, respectively, and was shorter in group 2. Duration of wound healing was statistically significantly different in the two groups. We concluded in this study that application of platelet-rich plasma in addition to laser pilonidoplasty significantly shortens the time of wound healing. Keywords Pilonidal sinus . Platelet-rich plasma . Laser pilonidoplasty . Wound healing
Introduction Pilonidal sinus disease (PSD) is a chronic inflammatory disease with a clinical course of recurrent inflammation and abscess in the natal cleft and sacrococcygeal area [1]. Hodges first created in 1880 the word “pilonidal” by combining the two words “pilus” and “nidus” which mean hair and nest in Latin, respectively [2]. Although it is more frequent in young
* Feyzi Kurt [email protected] 1
Adana Seyhan State Hospital, Adana, Turkey
2
Sözen Surgery Clinic, İstanbul, Turkey
3
University of Health Sciences Elazığ Fethi Sekin City Hospital, Elazığ, Turkey
4
Balıkesir Atatürk City Hospital, Balıkesir, Turkey
5
Istanbul Obesity Surgery (IOC) Clinic, Kurtköy Ersoy Hospital, İstanbul, Turkey
male adults, it can be seen in women and in both genders after 45 years of age, albeit rare [3]. The disease is a passive one, although the absolute etiology is unknown. Risk factors such as a positive family history, sedentary life style, and local trauma, being over hairy and White race, might be effective in the development of the disease [4]. The disease usually manifests in four forms. It might be asymptomatic, but
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