Effects and mechanism of platelet-rich plasma on military drill injury: a review
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REVIEW
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Effects and mechanism of platelet-rich plasma on military drill injury: a review Peng-Cheng Xu, Min Xuan and Biao Cheng*
Abstract Military drill injury is a significant part of military medical research. The increase of training intensity and changes in training methods lead to differences in injury types. The ideal therapeutic modality should allow rapid healing at a reasonable cost and minimize impact on patients’ life. Platelet -rich plasma (PRP), a platelet concentrate, is rich in a variety of growth factors and widely used clinically as a minimally invasive treatment. It plays an important role in injury repair and rehabilitation. In this article, we review the therapeutic role of PRP in military drill injury and its possible underlying mechanisms, with a focus on plantar fasciitis, stress fractures and other common injuries, in order to provide basic support for military reserve. Keywords: Military drill injury, Platelet- rich plasma (PRP), Plantar fasciitis, Stress fracture, Rehabilitation
Background Nowadays, military drill has become the main task of military work in the peace era. Strengthening actual combat military drill and improving the quality and level of troop training and preparation have become a new situation for army development, aiming at maintaining and improving troop combat readiness and effectiveness [1, 2]. With continuous intensification of military drill, the incidence of fatigue injuries, bone and joint injuries, ligament and other soft tissue injuries have gradually increased, leading to an increase in soldier disability rate and a decrease in attendance rate, which is very detrimental to the improvement of military force. It is considered that military drill injury has become a major threat to military reserve force [3]. Consequently, it is very necessary to find safer, more effective, and minimally invasive rehabilitation treatments to improve soldiers’ physical fitness and combat effectiveness. Platelet -rich plasma (PRP) is a platelet concentrate, consisting of a large number of growth factors and * Correspondence: [email protected] Department of Burn and Plastic Surgery, General Hospital of Southern Theater Command of Chinese PLA, No. 111 Liuhua Road, Yuexiu District, Guangzhou 510010, Guangdong Province, China
effective components [4], which can improve local microenvironment and promote tissue regeneration and repair [5, 6]. Recently, PRP has been widely used in clinical practice such as orthopedics [7], dermatology [8] and plastic surgery [9]. As a minimally invasive treatment, it has achieved good results in promoting wound healing, relieving the pain of osteoarthritis and providing some functional benefits. Basic and clinical studies have found that PRP has a good application prospect in the treatment of injuries. Therefore, in this article, we will review the possible role of PRP in the treatment of military drill injury.
Characteristics and application of PRP In 1954, Kingsley CS proposed the concept of PRP in Nature, and subsequently, the fun
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