Effects of platelet-rich fibrin and piezosurgery on impacted mandibular third molar surgery outcomes
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HEAD & FACE MEDICINE
RESEARCH
Open Access
Effects of platelet-rich fibrin and piezosurgery on impacted mandibular third molar surgery outcomes Lokman Onur Uyanık1, Kani Bilginaylar1* and İlker Etikan2 Abstract Introduction: The aim of this study was the comparision of postoperative outcomes in impacted mandibular third molars that were treated using either platelet-rich fibrin (PRF), a combination of PRF and piezosurgery, or conventional rotatory osteotomy. Patient and methods: The study included 20 patients; 40 extractions of impacted mandibular third molars were performed. Patients were divided into two main groups. In group A (n = 20), traditional surgery was performed on one side (Group 1, n = 10); traditional surgery was performed, and PRF was administered to the extracted socket on the other side of same patient (Group 2, n = 10). In group B (n = 20), on one side, piezosurgery was used for osteotomy, and PRF was administered (Group 3, n = 10); on the other side of same patient, traditional surgery was performed (Group 4, n = 10). Parameters assessed at baseline for each patient included pain, the number of analgesics taken, trismus, and cheek swelling. These variables were also assessed on postoperative days 1, 2, 3, and 7. Results: Statistical analysis revealed a significant reduction in postoperative pain (sum of 1st, 2nd, 3rd and 7th days) and trismus (on postoperative day 1) in group 2 (traditional surgery + PRF group), and in postoperative pain, the number of analgesics taken (sum of 1st, 2nd,3rd and 7th days) and trismus (on postoperative day 1) in group 3 (piezosurgery + PRF group) compared to groups 1 and 4 (traditional surgery groups), (p ≤ 0.05). However, swelling on postoperative days 1, 3, and 7 did not differ among the groups (p > 0.05). Only difference was on second day between groups 1–4 and 2–4 (p ≤ 0.05). Conclusions: The results of our study have shown that the use of PRF with traditional surgery and PRF combined with piezosurgery significantly reduced pain during the postoperative period. In addition, PRF in combination with piezosurgery significantly decreased the number of analgesics taken. Both operations also significantly decreased trismus 24 h after the surgery. As a result of this study, PRF and combination use of PRF and piezosurgery have positive effects in reducing postoperative outcomes after impacted third molar surgery. Keywords: Platelet-rich fibrin, Piezosurgery, Impacted third molar surgery, Pain, Swelling, Trismus
Introduction In oral surgery, impacted third molar surgery is one of the most common operations performed by oral and maxillofacial surgeons [1]. After the removal of impacted third molars, at the early postoperative periods, patients generally complain of pain, trismus and swelling which are the complications of this procedure [2, 3]. * Correspondence: [email protected] 1 Department of Oral and Maxillofacial Surgery, Near East University Faculty of Dentistry, Nicosia, Cyprus Full list of author information is available at the end of the article
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