Egesta Lopci, Stefano Fanti (Eds.): Atlas of Response to Immunotherapy
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BOOK REVIEW
Egesta Lopci, Stefano Fanti (Eds.): Atlas of Response to Immunotherapy Springer Nature Switzerland AG, 2020, ISBN 978-3-030-31113-1 Luigi Mansi 1
# Springer-Verlag GmbH Germany, part of Springer Nature 2020
Immunotherapy represents a new frontier in the fight against cancer, having the capability to cure otherwise incurable neoplasm, to improve prognosis in many oncologic patients, and to reach favorable results in terms of cost/effectiveness, mainly because of fewer negative collateral effects with respect to traditional therapy. Nevertheless, as for all innovative proposals, many issues have yet to be understood and standardized. Furthermore, because of the high cost, it is very important to have a priori information allowing to recruit only patients who will have benefit from the therapeutic strategy. In this context, it is also relevant to individuate as early as possible responders with respect to non-responders. This publication is one of the first publications in the field and is originally structured as an Atlas. It means that, in the 127 pages, the major relevance is attributed to the 111 illustrations, 100 of which in color. The aim is to present the most frequent patterns of response to immunotherapy applied in major oncologic settings, as they appear either on PET/CT or on conventional techniques, i.e., CT and MRI, representing actually the most diffuse standard in evaluating therapeutic response. The comparison between the molecular approach allowed by PET/CT and the morphostructural information given by alternative methods is an interesting way to better understand how to reach the highest diagnostic accuracy, individuating comparative signals permitting to acquire early correct information, avoiding false-positive results and pitfalls. Immune-related adverse events that may affect image interpretation are also described. To give an evaluation also on perspectives, the concluding chapter examines the
* Luigi Mansi [email protected] 1
Interuniversity Research Center for Sustainability (CIRPS), Naples, Italy
available data and potential developments of immuno-PET, considered the novel frontier of research in this oncological scenario. To reach the editorial goal, the analysis is performed on individual cases, accurately chosen in some of the worldwide widest and qualified case history of patients who underwent immunotherapy. The editors and the authors are internationally recognized between the major experts in Oncologic Diagnostic Imaging, with main reference to the advanced technologies applied to the most innovative research. Egesta Lopci is actually working in Nuclear Medicine at the Humanitas Clinical and Research Hospital-IRCCS in Rozzano (Milan), Italy. Stefano Fanti is a Full Professor of Diagnostic Imaging at the University of Bologna, Italy. The wide and deep practice of the authors in this specific field must be highlighted, because only really experienced imagers can identify and differentiate signals not yet well standardized or not easily identifiable. On the other ha
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