Endocrine Neoplasia
This group of pancreatic neoplasms is characterized by a predominant neuroendocrine differentiation. Over the years, the terminology and classification of endocrine neoplasia arising in the pancreas has undergone multiple changes. The WHO classification o
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Pathology of the Pancreas
Fiona Campbell • Caroline S. Verbeke
Pathology of the Pancreas A Practical Approach Second Edition
Fiona Campbell Department of Pathology Royal Liverpool University Hospital Liverpool UK
Caroline S. Verbeke Department of Pathology Oslo University Hospital University of Oslo Oslo Norway
ISBN 978-3-030-49847-4 ISBN 978-3-030-49848-1 (eBook) https://doi.org/10.1007/978-3-030-49848-1 © Springer Nature Switzerland AG 2021 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Preface
There have been many advances in pancreatic pathology since we wrote the first edition of this book. Emerging endoscopy and tissue sampling procedures, such as pancreatoscopy, micro-forceps biopsies, and fine-needle biopsies, are now being incorporated into routine diagnostic practice, and neoadjuvant therapy has become part of standard treatment. New diagnostic entities have been described, classifications and international guidelines have been updated, and molecular pathology is beginning to play a role in diagnostics and patient management. All of these advances have been incorporated into this new edition of the book. The book covers the spectrum of pancreatic pathology from congenital abnormalities and hereditary disorders to inflammatory disease and neoplasia, and it now also includes an entirely new chapter on pancreas transplant pathology (kindly provided by René Michel). There is also limited information on the small super-specialized area of pediatric pancreatic pathology, and the cytology chapter has been kindly revised by M. Priyanthi Kumarasinghe and Ian Yusoff. The book incorporates the recent WHO 2019 classification and TNM8, and brief summaries of the main molecula