Endocrine Neoplasia

Endocrine Neoplasia provides a broad overview of the neoplastic conditions of extracranial endocrine glands not involved in reproduction. Benign and malignant tumors of the thyroid, parathyroid glands, adrenals, and neuroendocrine pancreas are covere

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Cord Sturgeon Editor

Endocrine Neoplasia

Series Editor

Cancer Treatment and Research

Series Editor Steven T. Rosen Robert H. Lurie Comprehensive   Cancer Center Northwestern University Chicago, IL USA

For further volumes, go to http://www.springer.com/series/5808

Cord Sturgeon Editor

Endocrine Neoplasia



Editor Cord Sturgeon Northwestern University Feinberg School of Medicine Section of Endocrine Surgery Chicago, IL, USA [email protected]

ISSN 0927-3042 ISBN 978-1-4419-0856-8 e-ISBN 978-1-4419-0857-5 DOI 10.1007/978-1-4419-0857-5 Springer New York Dordrecht Heidelberg London Library of Congress Control Number: 2009940800 © Springer Science+Business Media, LLC 2010 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer ScienceþBusiness Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)

Preface

Endocrine neoplasms are fascinating tumors. Rare but usually dramatic diseases caused by the unchecked elaboration of hormones from endocrine fascinomas have been favorites of generations of medical students and professors alike. From an oncologic standpoint, endocrine tumors, even those arising from the same tissues, represent an amazingly heterogenous group of mostly indolent tumors (such as aldosteronoma or papillary thyroid cancer), with an occasional tumor of extraordinary malignant potential (such as adrenocortical carcinoma or anaplastic thyroid cancer). A detailed understanding of the biology of these tumors has allowed us to select the proper steps in treatment, before, during, and after surgery. There are many textbooks covering the subject of endocrine surgery, ranging from the comprehensive or specialized text to the abbreviated handbook. The purpose of this book is to describe the biology of disease and, within that context, discuss the proper clinical management of the endocrine tumors of the thyroid, parathyroid, pancreas, and adrenal glands. The book is divided into five sections addressing neoplasms of the thyroid, parathyroid, adrenal gland, neuroendocrine pan