Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity Ashok K. Singh
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e Schwinger–Keldysh time contour, the nonequilibrium equation of motion method, and the Kadanoff–Baym– Keldysh method. Chapter 8 discusses NGF methods for transport through nanosystems. Chapter 9 explores nonequilibrium problems involving vibronic effects as well as Coulomb blockade effects. There is a two-page index, and most of the book’s 77 illustrations add value. The author has done an excellent job of citing the original research literature; however, there are only a few reference citations for 2010, and none beyond that date. The book is heavily mathematical, and (as the author notes) requires some
Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity Ashok K. Singh Academic Press, 2016 554 pages, $93.75 (e-book $93.75) ISBN 9780128014066
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materials scientist working with new materials is often anxious about the product’s health effects. This book on engineered nanomaterials promises support in some of these questions with respect to nanoparticles. It gives indications about toxicity and the mechanisms of toxicity of nanomaterials, but it does not provide the average materials scientist with sufficient basic knowledge. As this topic is extremely complex, it is necessary to read at least a few chapters in detail to obtain the answers needed. Finally, this book is written for the professional development of toxicologists or students of this science. The book starts with a short, simple, and clear introduction to the basics of nanoparticles, namely their properties
and characterization. The introduction to “Nanotoxicology” is important to the engineer and materials scientist. The author explains that the conventional concept of a dose–response relationship based on the ratio between mass of the noxa (toxic substance) and body weight is no longer valid. Instead, one needs a new relation, taking into account the huge surface area of nanoparticles. However, such an indicator has been missing until now. The mechanisms of toxicity of nanoparticles are explained. Nanoparticles may have the potential to distribute in the whole human body; therefore, materials doing no harm as a bulk material to the human body may be highly toxic as a nanoparticle. In some cases, this behavior
prior understanding of theoretical physics, including quantum mechanics. Although the scientific problems discussed above are worked through in detail, no homework problems are provided. However, the book is useful for a graduate-level seminar class on nanoscale quantum transport and for self-study for experts working in this field. For those interested in nanoscale quantum transport, I recommend this book. Reviewer: Steven C. Moss is a senior scientist in the Electronics and Photonics Laboratory at The Aerospace Corporation in El Segundo, Calif., USA.
of nanoparticles is dangerous; however, using nanoparticles in addition to drugs may be the most important property and best approach (e.g., for cancer treatment). To verify these findings, the major part of the book describes the interaction of nanoparticles with proteins
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