Enzymes and Proteins from Thermophilic Microorganisms Structure and Function
LIST OF PARTICIPANTS 11 THERMOPHILIC HYDROLYTIC ENZYMES (PROTEINASES, AMYLASES) 17 Thermal Stability of Homologous Neutral Metalloendopeptidases in Thermo philic and Mesophilic Bacteria: Structural Considerations M. K. PANGBURN, P. L. LEVY, K. A. WALSH a
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Enzymes and Proteins from Thermophilic Microorganisms Structure and Function Proceedings of the International Symposium Zurich, July 28 to August 1, 1975 Edited by Herbert Zuber
Springer Basel AG
CIP-Kurztite1aufnahme der Deutschen Bibliothek Enzymes and proteins from thermophilic microorganisms: structure and function; proceedings of the internal. Symposium Ziirich, July 28 to August I, 19751 ed. by Herbert Zuber. - I. Aufl. - Basel, Stuttgart: Birkhauser, 1976. (Experientia: Suppl.; 26) NE: Zuber, Herbert [Hrsg.] All rights reserved No part of this book may be reproduced in any form, by photostat, microfilm, or any other means, without written permission from the publishers. © SpringerBaselAG 1976
Urspriinglich erschienen bei Birkhiluser Verlag Basel 1976 Softcover reprint of the hardcover 1st edition 1976 ISBN 978-3-0348-7677-3 ISBN 978-3-0348-7675-9 (eBook) DOl 10.1007/978-3-0348-7675-9
PRE F ACE
The papers collected in this volume were presented at the "Symposium on Enzymes and Proteins from Thermophilic Microorganisms" held in Zlirich, Switzerland, from July 28 - August 1, 1975. The phenomenon of life at higher temperatures, thermophily, has stimulated natural scientists for over twothousand years. Concern with this biological problem has experienced recurring renaissances over the centuries. Therefore, it is not surprising to find in our time when molecular biology radiates its influence into many disciplines of natural sciences and medicine, that the study of thermophily is again a central subject of interest and now from the molecular aspects. Together with nucleic acids, enzymes and other proteins are important molecules for the processes of life and they should in their thermophilic forms have an immediate relation to the phenomenon of thermophily. The structure and function of thermophilic enzymes and proteins has fascinated us for a long time in the laboratory and it occurred to us, about two years ago, their importance warranted discussion within a larger group. Thus we decided to organize a symposium. A preliminary inquiry that was circulated indicated to our pleasure great and spontaneous interest in the idea of holding such a symposium. Obviously there was a gap here that had not been filled by symposia already held on thermophilic microorganisms. The major purpose of this international meeting was to bring together for the first time scientists of several countries, joined by their common interest in the structure and properties of thermophilic enzymes and proteins and their importance to the complex processes of the thermophilic cell. Therefore, the object of attention was not restricted to the problem of thermostability, which is of course of considerable practical interest. A further purpose of this conference served to focus attention to this expanding area and it is hoped that this monograph will not only highlight the present frontiers and the accompanying problems, but will also serve as a useful reference source and as an entry into the field in general. Various aspects of the stru
