Essentials of Bioinformatics, Volume II In Silico Life Sciences: Med

Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting

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ls of Bioinformatics, Volume II In Silico Life Sciences: Medicine

Essentials of Bioinformatics, Volume II

Noor Ahmad Shaik  •  Khalid Rehman Hakeem Babajan Banaganapalli  •  Ramu Elango Editors

Essentials of Bioinformatics, Volume II In Silico Life Sciences: Medicine

Editors Noor Ahmad Shaik Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders Department of Genetic Medicine Faculty of Medicine King Abdulaziz University Jeddah, Saudi Arabia Babajan Banaganapalli Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders Department of Genetic Medicine Faculty of Medicine King Abdulaziz University Jeddah, Saudi Arabia

Khalid Rehman Hakeem Department of Biological Sciences King Abdulaziz University Jeddah, Saudi Arabia Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology King Abdulaziz University Jeddah, Saudi Arabia Ramu Elango Princess Al-Jawhara Center of Excellence in Research of Hereditary Disorders Department of Genetic Medicine Faculty of Medicine King Abdulaziz University Jeddah, Saudi Arabia

ISBN 978-3-030-18374-5    ISBN 978-3-030-18375-2 (eBook) https://doi.org/10.1007/978-3-030-18375-2 © Springer Nature Switzerland AG 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors, and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland

Dr. Ramu Elango dedicates the book to his wife, Karpagam; their children, Madhivanan and Ilankeeran; and his brothers, Govindan and Prof Krishnan Ramu and Anni-Vijaya Krishnan Dr. Babajan Banaganapalli dedicates the book to his family, Khader Basha, Shanu, Shanawaz, Shavar, and Shaju, wife, Gowsia; and their children, Rayyan and Reenah Dr. Noor Ahmad Shaik dedicates the book to his parents, Jan Ahmad and Abida Khatoon; siblings (Nazmul, J