Ethical Considerations in Performing Clinical Trials in and for Older People
In Europe, the population is ageing rapidly. Older people are taking many medicinal products daily, and these may not necessarily be suitable for them. According to research studies, older patients are underrepresented in clinical trials, especially those
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Sven Stegemann Editor
Developing Drug Products in an Aging Society From Concept to Prescribing
AAPS Advances in the Pharmaceutical Sciences Series Volume 24
Editors-in-chief Daan J.A. Crommelin, Utrecht University, Utrecht, The Netherlands Robert A. Lipper, Back Cove Pharma, LLC, Waldoboro, ME, USA
The AAPS Advances in the Pharmaceutical Sciences Series, published in partnership with the American Association of Pharmaceutical Scientists, is designed to deliver volumes authored by opinion leaders and authorities from around the globe, addressing innovations in drug research and development, and best practice for scientists and industry professionals in the pharma and biotech industries.
More information about this series at http://www.springer.com/series/8825
Sven Stegemann Editor
Developing Drug Products in an Aging Society From Concept to Prescribing
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Editor Sven Stegemann Graz University of Technology Graz Austria and Capsugel Bornem Belgium
ISSN 2210-7371 ISSN 2210-738X (electronic) AAPS Advances in the Pharmaceutical Sciences Series ISBN 978-3-319-43097-3 ISBN 978-3-319-43099-7 (eBook) DOI 10.1007/978-3-319-43099-7 Library of Congress Control Number: 2016946327 © American Association of Pharmaceutical Scientists 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Foreword 1
Medical and pharmaceutical sciences have substantially progressed in providing effective treatments against acute and chronic diseases. Along with increasing wealth, life expectancy has nearly doubled during the past century and many diseases have lost their terrifying nature. The increasing longevity and number of old and very old citizens in our society is a fundamental and important achievement of modern medicine that is beneficial to all of us. However, an aging society does not come without challenges, especially in providing
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