Etiology of Acute Leukemias in Children

Childhood acute leukemias are one of the main causes of death in children aged 1 to 14 years in some countries; and unfortunately, we have been unable to prevent it. Certainly, a good parcel of it is due to the poor understanding about its etiol

  • PDF / 5,257,579 Bytes
  • 332 Pages / 439.43 x 683.15 pts Page_size
  • 80 Downloads / 167 Views

DOWNLOAD

REPORT


123

Etiology of Acute Leukemias in Children

Juan Manuel Mejía-Aranguré Editor

Etiology of Acute Leukemias in Children

Editor Juan Manuel Mejía-Aranguré Coordinación de Investigación en Salud Instituto Mexicano del Seguro Social Ciudad de México México

ISBN 978-3-319-05797-2 ISBN 978-3-319-05798-9 DOI 10.1007/978-3-319-05798-9

(eBook)

Library of Congress Control Number: 2016935716 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Preface

Leukemias cause the greatest number of deaths of children in the developed world and some developing countries. Advances in the treatment of this disease laid the foundation for much of what is known today about the treatment of cancer. In some places in the world, survival rates of nearly 90 % have been attained for children with leukemia. Despite these enormous achievements, not all countries have been able to reach such survival rates for children with this disease. Even in countries where cure of this illness is most probable, the anxiety that accompanies a diagnosis of leukemia in the family and the suffering provoked by this disease underscore the great necessity of seeking measures to prevent this disease. However, it is difficult to prevent something when little is known about how and why it occurs. Nevertheless, in the history of medicine there have been examples showing that, despite not knowing with precision the cause of a disease, the fact of having a “theory” or a theoretical model that supposes the causes leading to the occurrence of that disease can lead to prevention of the illness. Such was the case of cholera in London in the time of John Snow (1813–1858). In the mid-nineteenth century the cause of cholera was not known, but Snow’s theoretical model of the pattern of outbreak o