Unclassifiable Leukemias
Jean BERNARD * I should like to begin with an assumption and a paradox. The assumption is that leukemia is a disease of a stem cell characterized by pathologie alterations of that cell and its progeny. All present research and discussions are centered aro
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Springer-Verlag Berlin Heidelberg NewYork 1975
Proceedings ofa Symposium, held on October 11-13,1974 at the Institute ofCell Pathology, Höpital de Bicetre, Paris, France
This monograph comprises the first issue of the new international journal Blood CeUs (Editor: Marcel Bessis, Associate Editor: Robert I. Weed) ISBN-13: 978-3-540-07242-3 e-ISBN-13: 978-3-642-66126-6 DOI: 10.1007/978-3-642-66126-6 This work is subject to copyright. All rights are reserved, wether the whole or part of the material is concemed, specifically those of translation, reprinting, re-use of illustrations, broadcastings, reproduction by photocopying machine or simitar means, and storage in data banks. Under § 54 of the German Copyright Law, where copies are made for other than private use, fee is payable to the publisher, the amount of the fee to be determined by agreement with the publisher.
© by Springer-Verlag Berlin Heidelberg 1975. Softcover reprint ofthe hardcover 1st edition 1975 The use of general descriptive names, trade names, trade marks etc. in this publication, even if the former are not especially identified, is not be taken as a sign that such names, as understood by the trade Marks and Merchandise Marks Act, may accordingly be used freely by anyone. Type-setting, printing and bookbinding: Universitätsdruckerei H. StürtzAG, Würzburg.
Table of Contents Section I: Present Practice of Classification, its Utility and Limitations Jean Bernard: Introduction . . . . . . . . . . . . . . . . . . . G. Flandrin, J ean Bernard : Cytological Classification of Acute Leukemias. A Survey of I 400 Cases . . . . . . . . . . . . . . . . . . . . . . . D.A.G.Galton, J.V.Dacie: Classification ofthe Acute Leukemias . . . .
3 7 17
G. Mathe, D. Belpomme, D. Dantchev, P. Pouillart, J.R. Schlumberger, M. Lafleur: Leukemic Lymphosarcomas: Respective Prognosis of the Three Types: Prolymphocytic, Lymphoblastic (or Lymphoblastoid) and Immunoblastic . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 G. Mathe, D. Belpomme, D. Dantchev, P. Pouillart, L. Navares, G. Hauss, J.R. Schlumberger, M. Lafleur: Search for Correlations between Cytological Types and Therapeutic Sensitivity of Acute Leukemias . 37 Answers to Submitted Questions .
53
Open DisClIssion of Section I
57
Section 11: New Techniques Used in Cytological Diagnosis L.G. Lajtha: Fluorescence Probe and Biochemical Characterization of Leukemic Cells . . . . . . . . . . . . . . . 63 Discussion . . . . . . . . . . . . . . . . . 67
B. Thorell: Automated Cell Population Analysis. Discussion . . . . . . . . . . . . . . . . . J.-c. Brouet, J.-L. Preud'Homme, M. Seligmann : Membrane Markers in the Classification of Human Reference to Acute Lymphoblastic Leukemia . . Discussion . . . . . . . . . . . . . . . . .
71 79 The Use of Band T Leukemias, with Special . . . . . . . . . . . 81 . . . . . . . . . . . 91
J.L. Binet, G. Dighiero,P.d'Athis, M. Feinermann,F.de Montaut, J. Seroude: Volumetric Determinations ofBlood Cells in Acute Lymphoblastic Leukemi
