Fabrication of bioactive corrosion-resistant polyaniline/TiO 2 nanotubes nanocomposite and their application in orthoped
- PDF / 3,262,361 Bytes
- 19 Pages / 595.276 x 790.866 pts Page_size
- 59 Downloads / 150 Views
Fabrication of bioactive corrosion-resistant polyaniline/ TiO2 nanotubes nanocomposite and their application in orthopedics Agilan Perumal1, Rahul Kanumuri2, Suresh Kumar Rayala2, and Rajendran Nallaiyan1,*
1 2
Department of Chemistry, CEG Campus, Anna University, Chennai, Tamil Nadu 600 025, India Department of Biotechnology, Indian Institute of Technology Madras, Chennai, Tamil Nadu 600 036, India
Received: 17 May 2020
ABSTRACT
Accepted: 18 July 2020
The long-term permanence of titanium implant was improved by incorporation of polyaniline on TiO2 nanotubes. The polyaniline incorporated TiO2 nanotubes (PANI-2/TNTA) has enhanced the bioactivity and corrosion resistance. Highly ordered nanotubes were formed on the titanium metal with an average tube diameter of * 85 nm which was confirmed by HR-SEM. The presence of anatase and rutile mixed phases was identified by XRD analysis. The formation of interfacial bonding between PANI and TNTA was confirmed by Raman and XPS analysis. The lower corrosion current density and higher polarization resistance (Rp) obtained for PANI-2/TNTA nanocomposite revealed the enhanced corrosion resistance behavior in physiological conditions. To ensure the durability of PANI-2/TNTA, the corrosion behavior was analyzed at different applied potentials using dynamic electrochemical impedance spectroscopy (DEIS). Up to 1 V, the higher impedance value was observed in Hanks’ solution. The bioactivity of the PANI-2/TNTA nanocomposite was confirmed by the more-notable cell adhesion and proliferation of MG-63 osteoblast-like cells. PANI-2/TNTA has the ability to reduce implant-associated infections. The existence of the amine group is responsible for better biostability and antimicrobial activity.
Ó
Springer Science+Business
Media, LLC, part of Springer Nature 2020
Address correspondence to E-mail: [email protected]; [email protected]
https://doi.org/10.1007/s10853-020-05079-3
J Mater Sci
GRAPHIC ABSTRACT
Introduction The increasing life span of human beings and the gradual increase in vehicular accidents have led to an increase in the frequency of osteoporotic induced fractures. This gradual increase demands more biocompatible and corrosion-resistant implant materials to efficiently promote stability and osseointegration. Metals and its alloys (titanium and its alloys, stainless steel, cobalt–chromium alloys) are used as long-term load-bearing orthopedic implant materials [1–3]. Among them, titanium and its alloys are well-known biomaterials due to their favorable physical, chemical and biological properties such as low elastic modulus, high strength–weight ratio, remarkable corrosion resistance and biocompatibility [4]. However, titanium implants are failed due to their bio-inertness, which lead to implant isolation from the surrounding bone by fibrous tissue encapsulation. Porous metallic implants have gained attention because they facilitate bone-bonding and improve the osteoblast growth on the implants [5, 6]. Nanostructured materials have been widely investigated fo
Data Loading...
