Fat-Soluble Vitamins

The subject for a volume on the fat-soluble vitamins needs no justification considering the importance of this group of nutrients and the rate of expan­ sion of our knowledge of its role in cell biology, genetics, and disease. The level of our understandi

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30

Fat-Soluble Vitamins

SUBCELLULAR BIOCHEMISTRY SERIES EDITOR J. ROBIN HARRIS, Institute of Zoology, University of Mainz, Mainz, Germany

ASSISTANT EDITORS H. 1. HILDERSON, University of Antwerp, Antwerp, Belgium B. B. BISWAS, University of Calcutta, Calcutta, India

Recent Volumes in This Series: Volume 21

Endoplasmic Reticulum Edited by N. Borgese and 1. R. Harris

Volume 22

Membrane Biogenesis Edited by A. H. Maddy and J. R. Harris

Volume 23

Physicochemical Methods in the Study of Biomembranes Edited by Herwig J. Hilderson and Gregory B. Ralston

Volume 24

Proteins: Structure, Function, and Engineering Edited by B. B. Biswas and Siddhartha Roy

Volume 25

Ascorbic Acid: Biochemistry and Biomedical Cell Biology

Edited by J. Robin Harris Volume 26

myo-Inositol Phosphates, Phosphoinositides, and Signal Transduction Edited by B. B. Biswas and Susweta Biswas

Volume 27

Biology of the Lysosome Edited by John B. Lloyd and Robert W. Mason

Volume 28

Cholesterol: Its Functions and Metabolism In Biology and Medicine Edited by Robert Bittman

Volume 29

Plant-Microbe Interactions Edited by B. B. Biswas and H. K. Das

Volume 30

Fat-Soluble Vitamins Edited by Peter J. Quinn and Valerian E. Kagan

A Continuation Order Plan is available for this series. A continuation order will bring delivery of each new volume immediately upon publication. Volumes are billed only upon actual shipment. For further information please contact the publisher.

Subcellular Biochemistry Volume

30

Fat-Soluble Vitamins Edited by

Peter J. Quinn King's College London University of London London. United Kingdom

and

Valerian E. Kagan University of Pittsburgh Pittsburgh. Pennsylvania

SPRINGER SCIENCE+BUSINESS MEDIA, LLC

The Library of Congress cataloged the first volume of this title as follows: Sub-cellular biochemistry. London, New York, Plenum Press, v. illus. 23 cm. quarterly. Began with Sept. 1971 issue. Cf. New serial titles. 1. Cytochemistry—Periodicals. 2. Cell organelles—Periodicals. QH611.S84 574.8'76

73-643479

ISSN 0306-0225 ISBN 978-1-4899-1791-1 ISBN 978-1-4899-1789-8 (eBook) DOI 10.1007/978-1-4899-1789-8 This series is a continuation of the journal Sub-Cellular Biochemistry, Volumes 1 to 4 of which were published quarterly from 1972 to 1975 © Springer Science+Business Media New York 1998 Originally published by Plenum Press, New York in 1998 Softcover reprint of the hardcover 1st edition 1998 http://www.plenum.com 1098765432 All rights reserved No part of this book may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording, or otherwise, without written permission from the Publisher

INTERNATIONAL ADVISORY EDITORIAL BOARD J. L. AVILA, Instituto de Biomedicina, Caracas, Venezuela R. BITTMAN, Queens College of The City University of New York, Flushing, New York, USA N. BORGESE, CNR Center for Cytopharmacology, University of Milan. Milan, Italy D. DASGUPTA, Saha Institute of Nuclear Physics, Calcutta, India H. ENGELHARDT, Ma