Water Soluble Vitamins Clinical Research and Future Application
The discovery of vitamins in the early 1900s, their later chemical characterization and the clarification of pivotal metabolic functions are sequential aspects of a brilliant chapter in the history of modern nutritional sciences and medicine. The name, de
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SUBCELLULAR BIOCHEMISTRY SERIES EDITOR J. ROBIN HARRIS, University of Mainz, Mainz, Germany
ASSISTANT EDITORS B.B. BISWAS, University of Calcutta, Calcutta, India P. QUINN, King’s College London, London, UK Recent Volumes in this Series Volume 41
Chromatic and Disease Edited by Tapas K. Kundu and Dipak Dasgupta
Volume 42
Inflammation in the Pathogenesis of Chronic Disease Edited by Randall E. Harris
Volume 43
Subcellular Proteomics Edited by Eric Bertrand and Michel Faupel
Volume 44
Peroxiredoxin Systems Edited by Leopold Folhé and J. Robin Harris
Volume 45
Calcium Signalling and Disease Edited by Ernesto Carafoli and Marisa Brini
Volume 46
Creatine and Creatine Kinase in Health and Disease Edited by Gajja S. Salomons and Markus Wyss
Volume 47
Molecular Mechanisms of Parasite Invasion Edited by Barbara A. Burleigh and Dominique Soldati-Favre
Volume 48
The Cronin Family of Proteins Edited by Christoph S. Clemen and Ludwig Eichinger
Volume 49
Lipids in Health and Disease Edited by Peter J. Quinn and Xiaoyuan Wang
Volume 50
Genome Stability and Human Diseases Edited by Heinz-Peter Nasheuer
Volume 51
Cholesterol Binding and Cholesterol Transport Proteins Edited by Robin J. Harris
Volume 52
A Handbook of Transcription Factors Edited by Tim Hughes
Volume 53
Endotoxins: Stricture, Function and Recognition Edited by Xiaoyuan Wang and Peter J. Quinn
Volume 54
Conjugation and Deconjugation of Ubiquitin Family Modifiers Edited by Marcus Groettrup
Volume 55
Purinergic Regulation of Respiratory Diseases Edited by Maryse Picher and Richard C. Boucher
Olaf Stanger Editor
Water Soluble Vitamins Clinical Research and Future Application
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Editor Olaf Stanger, MD, PhD, MBA Royal Brompton and Harefield NHS Foundation Imperial College of Science, Technology and Medicine Heart Division Cardiothoracic Surgery Sydney Street London SW3 6NP United Kingdom [email protected]
ISSN 0306-0225 ISBN 978-94-007-2198-2 e-ISBN 978-94-007-2199-9 DOI 10.1007/978-94-007-2199-9 Springer Dordrecht Heidelberg London New York Library of Congress Control Number: 2011936736 © Springer Science+Business Media B.V. 2012 No part of this work may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, microfilming, recording or otherwise, without written permission from the Publisher, with the exception of any material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Printed on acid-free paper Springer is part of Springer Science+Business Media (www.springer.com)
INTERNATIONAL ADVISORY EDITORIAL BOARD R. Bittman, Queens College, City University of New York, New York, USA D. Dasgupt, Saha Institute of Nuclear Physics, Calcutta, India A. Holzenburg, Texas A&M University, Texas, USA S. Rottem, The Hebrew University, Jerusalem, Israel M. Wyss, DSM Nutritional Products Ltd., Basel, Switzerland
Preface
For many years, there were vague ideas that some diseases were
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