First patient management of COVID-19 in Changsha, China: a case report
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CASE REPORT
Open Access
First patient management of COVID-19 in Changsha, China: a case report Jian Zhou1†, Ziqin Cao1†, Wanchun Wang1, Kang Huang2, Fang Zheng2, Yuanlin Xie2, Dixuan Jiang2* and Zhiguo Zhou2*
Abstract Background: In December 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, Hubei Province, China. It rapidly spread and many cases were identified in multiple countries, posing a global health problem. Here, we report the first patient cured of COVID-19 infection in Changsha, China, and the symptoms, diagnosis, treatment, and management of this patient are all described in this report. Case presentation: A 57-year-old woman developed cough and fever after returning to Changsha from Wuhan on January 9, 2020. She tested positive for COVID-19 infection, a diagnosis which was supported by chest CT. The patient was treated with lopinavir and ritonavir tablets and interferon alfa-2b injection. A low dose of glucocorticoids was used for a short period to control bilateral lung immune response, and this patient avoided being crushed by cytokine storms that might have occurred. The clinical condition of this patient improved, and a COVID-19 assay conducted on January 25, 2020 generated negative results. This patient recovered and was discharged on January 30, 2020. Conclusions: Currently, there are numerous reports on COVID-19 infections focusing on the disease’s epidemiological and clinical characteristics. This case describes the symptoms, diagnosis, treatment, and management of a patient cured of COVID-19 infection, which may serve as reference for future cases, while further studies are needed. Keywords: Cured patient, COVID-19, China, Case report
Background Coronavirus disease 2019 (COVID-19) infections can lead to severe respiratory disease. At the beginning of December 2019, a cluster of patients with COVID-19 infection was reported in China [1, 2, 3]. A previous report on COVID-19 indicated that human-to-human transmission of COVID-19 had been occurring [4]. By August 31, 2020, a cumulative total of nearly 25 million cases and 800,000 deaths have been reported [5].
COVID-19’sepidemiological clinical features were reported in several studies [4, 6, 7]. The first case of COVID-19 infection in the United States was reported on January 20, 2020, and the clinical condition of this patient apparently improved following treatment with intravenous remdesivir [8]. In this report, we describe the symptoms, diagnosis, treatment, and management of the first patient cured of COVID-19 infection in Changsha, China.
* Correspondence: [email protected]; [email protected] † Jian Zhou and Ziqin Cao contributed equally to this work. 2 Department of Respiratory Medicine, The First Hospital of Changsha City, No.311 Yingpan Road, Kaifu District, Changsha 410005, Hunan Province, China Full list of author information is available at the end of the article
Case presentation On January 16, 2020, a 57-year-old woman came to the emergency department of the First Hospital of Changsha City, China. After 1
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