Fish Vaccines
This book provides a useful text for research students and scientists on the latest knowledge about the immune system of fish, cutting edge technologies and the step required to develop, test and commercialise fish vaccines. It brings together information
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Alexandra Adams Editor
Fish Vaccines
Birkhäuser Advances in Infectious Diseases Series editors Stefan H.E. Kaufmann Max Planck Institute for Infection Biology, Berlin, Germany Andrew A. Mercer Department of Microbiology and Immunology, University of Otago Dunedin, New Zealand Olaf Weber Bonn, Germany
More information about this series at http://www.springer.com/series/5444
Alexandra Adams Editor
Fish Vaccines
Editor Alexandra Adams University of Stirling Institute of Aquaculture, Faculty of Natural Sciences Stirling UK
Birkhäuser Advances in Infectious Diseases ISBN 978-3-0348-0978-8 ISBN 978-3-0348-0980-1 DOI 10.1007/978-3-0348-0980-1
(eBook)
Library of Congress Control Number: 2016956092 © Springer Basel 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This book is published under the trade name Birkhäuser, www.birkhauser-science.com
Contents
1
Fish Disease Causing Economic Impact in Global Aquaculture . . . . . . 1 Hamish D. Rodger
2
Overview of the Fish Adaptive Immune System . . . . . . . . . . . . . . . . . . 35 Chris J. Secombes and Rodrigo Belmonte
3
Development of Fish Vaccines: Focusing on Methods . . . . . . . . . . . . . . 53 Øystein Evensen
4
Adjuvants and Delivery Methods: Current and Novel . . . . . . . . . . . . . 75 Roy Dalmo, Jarl Bøgwald, and Carolina Tafalla
5
Fish Vaccines: The Regulatory Process and Requirements from the Laboratory Bench to a Final Commercial Product, Including Field Trials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105 Gillian Cowan, P. Smith, and P. Christofilogiannis
6
Methods for Measuring Efficacy, Safety and Potency of Fish Vaccines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 Paul J. Midtlyng
7
Potential of DIVA Vaccines for Fish . . . . . . . . . . . . . . . . . . . . . . . . . . . 143 Sean J. Monaghan, Kim D. Thompson, Patrick D. Smith, and Alexandra Adams
Index . . . . . . . . . . . . . .
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