Frailty and mortality: an 18-year follow-up study among Finnish community-dwelling older people
- PDF / 699,780 Bytes
- 7 Pages / 595.276 x 790.866 pts Page_size
- 120 Downloads / 218 Views
ORIGINAL ARTICLE
Frailty and mortality: an 18‑year follow‑up study among Finnish community‑dwelling older people Marika Salminen1,2 · Anna Viljanen3,4 · Sini Eloranta5,6 · Paula Viikari1,3 · Maarit Wuorela1,3 · Tero Vahlberg7 · Raimo Isoaho2,8 · Sirkka‑Liisa Kivelä2,9 · Päivi Korhonen2 · Kerttu Irjala10 · Minna Löppönen11 · Laura Viikari1,3 Received: 26 August 2019 / Accepted: 11 October 2019 © The Author(s) 2019
Abstract Background There is a lack of agreement about applicable instrument to screen frailty in clinical settings. Aims To analyze the association between frailty and mortality in Finnish community-dwelling older people. Methods This was a prospective study with 10- and 18-year follow-ups. Frailty was assessed using FRAIL scale (FS) (n = 1152), Rockwood’s frailty index (FI) (n = 1126), and PRISMA-7 (n = 1124). To analyze the association between frailty and mortality, Cox regression model was used. Results Prevalence of frailty varied from 2 to 24% based on the index used. In unadjusted models, frailty was associated with higher mortality according to FS (hazard ratio 7.96 [95% confidence interval 5.10–12.41] in 10-year follow-up, and 6.32 [4.17–9.57] in 18-year follow-up) and FI (5.97 [4.13–8.64], and 3.95 [3.16–4.94], respectively) in both follow-ups. Also being pre-frail was associated with higher mortality according to both indexes in both follow-ups (FS 2.19 [1.78–2.69], and 1.69 [1.46–1.96]; FI 1.81[1.25–2.62], and 1.31 [1.07–1.61], respectively). Associations persisted even after adjustments. Also according to PRISMA-7, a binary index (robust or frail), frailty was associated with higher mortality in 10- (4.41 [3.55–5.34]) and 18-year follow-ups (3.78 [3.19–4.49]). Discussion Frailty was associated with higher mortality risk according to all three frailty screening instrument used. Simple and fast frailty indexes, FS and PRISMA-7, seemed to be comparable with a multidimensional time-consuming FI in predicting mortality among community-dwelling Finnish older people. Conclusions FS and PRISMA-7 are applicable frailty screening instruments in clinical setting among community-dwelling Finnish older people. Keywords Association · Frailty · Mortality · Older people Electronic supplementary material The online version of this article (https://doi.org/10.1007/s40520-019-01383-4) contains supplementary material, which is available to authorized users. * Marika Salminen [email protected] 1
City of Turku, Welfare Division, Yliopistonkatu 30, 20101 Turku, Finland
Faculty of Medicine, Department of Clinical Medicine, Unit of Family Medicine, University of Turku, 20014 Turku, Finland
2
3
Faculty of Medicine, Department of Clinical Medicine, Unit of Geriatrics, University of Turku, Turku City Hospital, Kunnallissairaalantie 20, 20700 Turku, Finland
4
Municipality of Lieto Health Care Centre, Hyvättyläntie 7, 21420 Lieto, Finland
5
Faculty of Medicine, Department of Nursing Science, University of Turku, 20014 Turku, Finland
6
Turku University of Applied Science, Health and Well-b
Data Loading...
