Ganglioside Biochemistry
This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry. The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc
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Ganglioside Biochemistry
Ganglioside Biochemistry
Cheorl-Ho Kim
Ganglioside Biochemistry
Cheorl-Ho Kim Molecular and Cellular Glycobiology Lab SungKyunKwan University Suwon, Korea (Republic of)
ISBN 978-981-15-5814-6 ISBN 978-981-15-5815-3 https://doi.org/10.1007/978-981-15-5815-3
(eBook)
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Preface
Carbohydrates: The Third Life Chain Organisms whether prokaryotes or eukaryotes intracellularly biosynthesize their fundamental molecules, which are basically important for their polymeric building blocks, using C, H, O, and N as the main atoms as well as P and S as functional atoms. For the fulfillment of the biosynthetic backbone, they generate nucleotides as components of polymeric nucleic acids, amino acids for protein constituents, monosaccharides for multiple carbohydrate polymers, and fatty acids for lipids and lipid derivatives. These are used as the primary donors of macromolecular building blocks of living organisms. Until now, only two major components of nucleic acids and amino acids have been particularly studied for their roles and functions in life chains. The structure, biosynthesis, function, and intracellular signaling of DNA/RNA and proteins have achieved tremendous progress and understanding of life. Interestingly from the 1990s, carbohydrates or glycans have become a new subject in understanding of life, and consequently, they have gained recognition as molecules of the third life chain, especially in eukaryotes. Unlike proteins and nucleic acids, carbohydrates are an enigmatic field in life science and biology. Currently, our knowledge of biological scie
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