Gastrointestinal Symptoms Onset in COVID-19 Patients in Wuhan, China
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ORIGINAL ARTICLE
Gastrointestinal Symptoms Onset in COVID‑19 Patients in Wuhan, China Ping An1,2,3 · Hongbin Chen4 · Haixia Ren1,2,3 · Juan Su1,2,3 · Mengyao Ji1,2,3 · Jian Kang1,2,3 · Xiaoda Jiang1,2,3 · Yifei Yang5 · Jiao Li1,2,3 · Xiaoguang Lv1,2,3 · Anning Yin1,2,3 · Di Chen1,2,3 · Mingkai Chen1,2,3 · Zhongyin Zhou1,2,3 · Weiguo Dong1,2,3 · Yijuan Ding1,2,3 · Honggang Yu1,2,3 Received: 16 April 2020 / Accepted: 22 October 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Background Early detection is critical in limiting the spread of 2019 novel coronavirus (COVID-19). Although previous data revealed characteristics of GI symptoms in COVID-19, for patients with only GI symptoms onset, their diagnostic process and potential transmission risk are still unclear. Methods We retrospectively reviewed 205 COVID-19 cases from January 16 to March 30, 2020, in Renmin Hospital of Wuhan University. All patients were confirmed by virus nuclei acid tests. The clinical features and laboratory and chest tomographic (CT) data were recorded and analyzed. Results A total of 171 patients with classic symptoms (group A) and 34 patients with only GI symptoms (group B) were included. In patients with classical COVID-19 symptoms, GI symptoms occurred more frequently in severe cases compared to non-severe cases (20/43 vs. 91/128, respectively, p
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