Genetic Pathways to Human Cancer
Carcinogenesis is a multi-step process and it is generally accepted that morphological changes that occur in malignant progression reflect the sequential acquisition of genetic alterations. Sequences of genetic alterations appear to be tissue- and cell ty
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Volume 156 Editor-in-Chief K. Starke, Freiburg i. Br. Editorial Board G.Y.R. Born, London M. Eichelbaum, Stuttgart D. Ganten, Berlin H . Herken, Berlin F. Hofmann, Miinchen L. Limbird, Nashville, TN W. Rosenthal, Berlin G. Rubanyi, Richmond, CA
Springer-Verlag Berlin Heidelberg GmbH
Mechanisms in Carcinogenesis and Cancer Prevention Contributors
1.U. Ali, EX. Bosch, N. Frank, C. Gerhauser, C.A. Gonzales, E. Gormally, P. Hainaut, K. Hemminki, E . Hietanen', L.M . Howells, E.A. Hudson, R . Kaaks, G. Kelloff, E Lyko, M. Manson, H. Ohgaki, H . Ohshima, O. Pelkonen, P. Peltomaki, H. Raunio, 1. Ribes, S. De Sanjose, c.c. Sigman, B. Stewart, M.Tatemichi, K. Vahakangas, H . Vainio, Z.-Q. Wang, C. Wild, W. Yasui, 1. Yokota
Editors HARRI
U. VAINIO and
Springer
EINO
K. HIETANEN t
H.
VAINIO
Unit of Chemoprevention International Agency for Research on Cancer 150, cours Albert-Thomas 69372 Lyon France e-mail: [email protected]
E. HIETANEN t
With 30 Figures and 24 Tables ISBN 978-3-642-07859-0 DOI 10.1007/978-3-662-08602-5
ISBN 978-3-662-08602-5 (eBook)
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Eino Hietanen (13.10.1947-16.09.2002) This book is dedicated to my long-time friend, Eino Hietanen, MD, PhD, who passed away unexpectedly on September 16th , 2002. Eino was a compassionate physician and a steadfast and innovative toxicologist with deep understanding of research and commitment to better protect people from envi
