Giant choroid plexus cysts with calvarial erosion: a case report and literature review
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CASE REPORT
Giant choroid plexus cysts with calvarial erosion: a case report and literature review Runze Yang 1 & Han Yan 2,3 & Michael C. Dewan 4 & Jignesh K. Tailor 3 & Sakun Santisukwongchote 5 & Cynthia Hawkins 5,6 & George M. Ibrahim 2,3,7 Received: 5 August 2020 / Accepted: 12 October 2020 # Springer-Verlag GmbH Germany, part of Springer Nature 2020
Abstract Choroid plexus cysts rarely grow to be symptomatic. Few large choroid plexus cysts have been reported in the pediatric population. The authors report a 15-month-old boy with increased head circumference and a bony deformity in the left parietal region due to mass effect from a giant choroid plexus cyst. The child had a craniotomy for open resection of the cyst, and made an excellent recovery. The differential diagnosis for intraventricular cysts and the literature surrounding choroid plexus cysts are discussed. Keywords Choroid plexus cyst . Complex intraventricular cysts . Giant intraventricular cyst . Increased head circumference
Introduction Complex intraventricular cysts of the brain are uncommon in children and challenging to manage. The differential diagnosis may include neoplasms, infectious cysts such as neurocysticercosis and hydatid cysts, and sterile lesions including arachnoid cysts and choroid plexus cysts. Here, we describe a case of a 15-month-old boy with a giant intraventricular cyst that was confirmed to be a choroid plexus cyst on histology. We discuss the unusual case presentation, our surgical approach, and
* George M. Ibrahim [email protected] 1
Cumming School of Medicine, University of Calgary, Calagary, Canada
2
Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Canada
3
Division of Neurosurgery, Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada
4
Division of Neurosurgery, Vanderbilt University, Nashville, TN, USA
5
Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, Canada
6
Arthur and Sonia Labatt Brain Tumour Research Center, Hospital for Sick Children, Toronto, ON, Canada
7
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada
the literature surrounding choroid plexus cysts in the pediatric population.
Case presentation A 15-month-old boy was referred to the Hospital for Sick Children for macrocephaly and calvarial asymmetry. The parents noticed a bump on the head at 8 months of age, which slowly increased in size and was associated with mild discomfort on palpation. He demonstrated no other signs or symptoms of hydrocephalus or elevated intracranial pressure, and a review of systems was unremarkable. His prenatal course was unremarkable, and his prenatal ultrasound showed no appreciable abnormalities. There was no remarkable travel history or infectious history. The clinical exam revealed a boy with a normal phenotype who did not show any obvious focal neurological deficits or symptoms of hydrocephalus other than an increased head circumference (51.5 cm, 99 percentile). There w
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