Hematologic Abnormalities and Acute Lung Syndromes
This book provides a unique frame work for examining acute lung syndromes that arise from hematologic disorders or is defined by a hematologic abnormality as a key feature. Acute lung processes arising from hematologic disorders can present as life-
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Janet S. Lee Michael P. Donahoe Editors
Hematologic Abnormalities and Acute Lung Syndromes
Respiratory Medicine Series Editor: Sharon I.S. Rounds
More information about this series at http://www.springer.com/series/7665
Janet S. Lee • Michael P. Donahoe Editors
Hematologic Abnormalities and Acute Lung Syndromes
Editors Janet S. Lee, MD Professor of Medicine Division of Pulmonary, Allergy, and Critical Care Medicine Department of Medicine University of Pittsburgh School of Medicine Pittsburgh, PA, USA
Michael P. Donahoe, MD Professor of Medicine Division of Pulmonary, Allergy, and Critical Care Medicine Department of Medicine University of Pittsburgh School of Medicine Pittsburgh, PA, USA
ISSN 2197-7372 ISSN 2197-7380 (electronic) Respiratory Medicine ISBN 978-3-319-41910-7 ISBN 978-3-319-41912-1 (eBook) DOI 10.1007/978-3-319-41912-1 Library of Congress Control Number: 2016951643 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Humana Press imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland
Preface
Standard textbooks in Respiratory Medicine do not typically organize their contents to specifically address hematologic abnormalities in acute lung syndromes. However, the main function of the lung is gas exchange at the interface between the external environment and blood. Thus, by definition, blood and its components are an integral part of the lungs and, given the large surface area of the pulmonary vascular beds, the lungs harbor a significant fraction of the circulating blood volume at any one time. While red cells are the vehicles for gas transfer, platelets provide hemostasis, and leukocytes vital for lung homeostasis and immunity, components of the hematopoietic system, can also serve as agents of injury to the lungs in disease states. So, it is not surprising that primary hematologic disorders or disorders secondary to
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