Hepatocyte paraffin 1 and arginase-1 are effective panel of markers in HBV-related HCC diagnosis in fine-needle aspirati
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BMC Research Notes Open Access
RESEARCH NOTE
Hepatocyte paraffin 1 and arginase‑1 are effective panel of markers in HBV‑related HCC diagnosis in fine‑needle aspiration specimens Bita Moudi1,2 , Hamidreza Mahmoudzadeh‑Sagheb1,2 and Zahra Heidari1,2*
Abstract Objective: In order to make successful treatment for HBV-related hepatocellular carcinoma, an early diagnosis is necessary. In this research we aimed to evaluate the IHC staining pattern of Hepatocyte paraffin 1 and arginase-1 and their performance in early diagnosis of HCC. The incidence of HepPar-1 and Arg-1 were evaluated by IHC in 121 patients (HBV, HCC, HBV + HCC) and 30 healthy subjects. Results: Arg-1 had significantly increased sensitivity in identification of HBV + HCC patients compared to Hep‑ Par-1 (P
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