Human Cytomegalovirus
The earliest observation of cytomegalovirus (CMV) interactions with the host cell was owl eye cytopathology in various tissues. It was recognized in the early 1970s that human CMV caused in utero infections resulting in congenital brain damage and other s
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Thomas Shenk Mark F. Stinski Editors
Human Cytomegalovirus
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Current Topics in Microbiology and Immunology Volume 325
Series Editors Richard W. Compans Emory University School of Medicine, Department of Microbiology and Immunology, 3001 Rollins Research Center, Atlanta, GA 30322, USA Max D. Cooper Department of Pathology and Laboratory Medicine, Georgia Research Alliance, Emory University, 1462 Clifton Road, Atlanta, GA 30322, USA Tasuku Honjo Department of Medical Chemistry, Kyoto University, Faculty of Medicine, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan Hilary Koprowski Thomas Jefferson University, Department of Cancer Biology, Biotechnology Foundation Laboratories, 1020 Locust Street, Suite M85 JAH, Philadelphia, PA 19107-6799, USA Fritz Melchers Biozentrum, Department of Cell Biology, University of Basel, Klingelbergstr. 50–70, 4056 Basel Switzerland Michael B.A. Oldstone Department of Neuropharmacology, Division of Virology, The Scripps Research Institute, 10550 N. Torrey Pines, La Jolla, CA 92037, USA Sjur Olsnes Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello 0310 Oslo, Norway Peter K. Vogt The Scripps Research Institute, Dept. of Molecular & Exp. Medicine, Division of Oncovirology, 10550 N. Torrey Pines. BCC-239, La Jolla, CA 92037, USA
Thomas E. Shenk • Mark F. Stinski Editors
Human Cytomegalovirus
Editors Thomas E. Shenk Princeton University Princeton, NJ 08544-1014 USA [email protected]
Mark F. Stinski University of Iowa Iowa City, IA 52242 USA [email protected]
Cover Illustration: HCMV infected HFF (3 h p.i.). Green dots outside the blue stained nucleus represent pp71 antibodies bound to viral particles. Larger green dots in the (blue) nucleus represent pp71 antibodies bound to Daxx, which is associated with PML at ND10. The three red domains located beside the pp71 stained ND10 denote the localization of IE2 aggregates. Figure from G. Maul, this volume.
ISBN 978-3-540-77348-1 e-ISBN 978-3-540-77349-8 DOI 10.1007/978-3-540-77349-8 Current Topics in Microbiology and Immunology ISSN 0070-217x Library of Congress Catalog Number: 2008920670 © 2008 Springer-Verlag Berlin Heidelberg This work is subject to copyright. All rights reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September, 9, 1965, in its current version, and permission for use must always be obtained from Springer-Verlag. Violations are liable for prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Product lia
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