Imaging Accuracy in Diagnosis of Different Focal Liver Lesions: A Retrospective Study in North of Iran
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ORIGINAL RESEARCH
Imaging Accuracy in Diagnosis of Different Focal Liver Lesions: A Retrospective Study in North of Iran Ahmad Alizadeh 1 & Fariborz Mansour-Ghanaei 2 & Faezeh Berengi Bagheri 3 & Hossein Froutan 4 & Yaser Froutan 5 & Farahnaz Joukar 1 & Zahra Atrkar-Roushan 6 & Seyed Ali Chavoshi 7 & Soheil Hassanipour 8
# Springer Science+Business Media, LLC, part of Springer Nature 2020
Abstract Introduction Focal liver lesions (FLLs) are incidentally detected masses found in daily abdominal imaging which are necessary to be characterized, because of the potential of being malignant. There are several imaging methods, such as ultrasonography (US), computed tomography (CT scan), and contrast enhanced magnetic resonance imaging (MRI). Here, we evaluate and compare the diagnostic accuracy (i.e., sensitivity and specificity) of these imaging methods for the diagnosis of FLLs. Material and Methods In this retrospective study, patients with focal liver lesions included and based on the gastroenterologist decision, in 79 patients different imaging methods were used to determine the nature of FLLs: the US, CT scan, and MRI. At the next step, fine-needle aspiration biopsy (FNA) was performed in all cases, and the results about the true nature of FLLs compared with different imaging results. The chi-square test and McNemar test were used. Results Ultrasound diagnosis of benign and malignant was obtained with 82% diagnosis accuracy, 100% sensitivity, 71.4% specificity, 100% negative predictive value, and 69.2% positive predictive value (PPV) compared with the biopsy. Also, the results of benign and malignant masses in CT scan were obtained with diagnostic accuracy of 95%, 100% sensitivity, 80% specificity, 93.9% positive predictive value, and 100% negative predictive value. MRI performed only in 2 cases with similar results to pathology. Conclusion It seems that CT scan is more appropriate and useful in the diagnosis of hepatic masses due to its higher diagnostic accuracy than the ultrasound. Keywords Biopsy . Ultrasound . CT scan . Focal liver lesions . Sensitivity . Specificity
* Fariborz Mansour-Ghanaei [email protected] 1
Caspian Digestive Disease Research Center, Guilan University of Medical Sciences, Rasht, Iran
2
Gastrointestinal and Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran
3
Department of Radiology, Poursina Hospital, Guilan University of Medical Sciences, Rasht, Iran
4
Emam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
5
Department of Pathology, Guilan University of Medical Sciences, Rasht, Iran
6
School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
7
Department of Radiology, Shahid Beheshti Hospital, Qom University of Medical Sciences, Qom, Iran
8
GI Cancer Screening and Prevention Research Center, Guilan University of Medical Sciences, Rasht, Iran
Introduction Focal liver lesions (FLLs) are incidentally detected masses found in daily abdominal imaging which are necessary to be characterized, because of
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