Imaging and Diagnosis in Pediatric Brain Tumor Studies
This book describes the features in structural imaging of the most important pediatric brain tumors with the aim of enabling radiologists to make the correct differential diagnosis and to provide the pediatric oncologist with all the imaging information r
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Monika Warmuth-Metz
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Imaging and Diagnosis in Pediatric Brain Tumor Studies
Monika Warmuth-Metz
Imaging and Diagnosis in Pediatric Brain Tumor Studies
Monika Warmuth-Metz Neuroradiology Universityhospital Würzburg Würzburg Germany Contributing author Stefan Rutkowski Department of Pediatric Oncology and Hematology HIT-MED-Study Center University Hospital of Hamburg Eppendorf Hamburg Germany
ISBN 978-3-319-42501-6 ISBN 978-3-319-42503-0 DOI 10.1007/978-3-319-42503-0
(eBook)
Library of Congress Control Number: 2016955081 © Springer International Publishing Switzerland 2017 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper This Springer imprint is published by Springer Nature The registered company is Springer International Publishing AG Switzerland The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland
Foreword
Once the modern era of neurosurgery began nearly a century ago, it became evident that a uniform system of classifying and grading brain tumors would be invaluable in guiding therapeutic decisions and comparing the relative efficacy of different treatment regimens. A number of schemas were adopted, some widely, some idiosyncratic, and others limited to one or a small group of institutions. No worldwide standard existed until the World Health Organization (WHO) began convening a panel of expert neuropathologists with the goal of developing a uniform, internationally-recognized system that could be applied across different institutions. Beginning in 1986, the WHO Classification of CNS Neoplasms rapidly became the worldwide reference standard. It has been updated approximately every 7 years, with the fourth edition published in 2007 and the “4-plus” edition just published in May, 2016. Brain tumor trials that evaluate efficacy of different treatment regimens are largely based on the WHO classification system. As imaging has become increasingly more sophisticated, it has become an integral part of brain tumor d
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