Immunohematology and Transfusion Medicine A Case Study Approach

This volume is a collection of immunohematology and transfusion medicine cases, comprised of clinical vignettes and antibody panels with questions based on each case, arranged in a workbook format. The cases are based on real patient problems which are ty

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Mark T. Friedman • Kamille A. West  Peyman Bizargity

Immunohematology and Transfusion Medicine A Case Study Approach

Mark T. Friedman St. Luke’s-Roosevelt Hospital and Beth Israel Medical Centers Department of Pathology, Blood Bank and Transfusion Service The Mount Sinai Health System New York New York USA

Peyman Bizargity St. Luke’s-Roosevelt Hospital and Beth Israel Medical Centers Department of Pathology The Mount Sinai Health System New York New York USA

Kamille A. West Department of Transfusion Medicine National Institutes of Health Clinical Center Bethesda Maryland USA

The views expressed do not necessarily represent the views of the National Institutes of Health, the Department of Health and Human Services, or the U.S. Federal Government. ISBN 978-3-319-22341-4       ISBN 978-3-319-22342-1 (eBook) DOI 10.1007/978-3-319-22342-1 Library of Congress Control Number: 2015945233 Springer Cham Heidelberg New York Dordrecht London © Springer International Publishing Switzerland 2016 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. Printed on acid-free paper Springer International Publishing AG Switzerland is part of Springer Science+Business Media (www.springer.com)

Preface

Pre-transfusion testing, including ABO/Rh typing, identification of unexpected antibodies, and compatibility testing, is an important measure in the provision of blood that may be transfused to the patient in the safest possible manner. This brief introduction is not intended to give the trainee a detailed instruction on solving immunohematology cases; rather, it is intended to give an overview on how to approach the immunohematology problems (Chaps. 1–28) of this workbook. The authors of this workbook presume that the reader has had at least basic instruction in immunohematology before engaging in these cases. Although one may be tempted to jump right to the antibody panel after noting a positive antibody screen in the presented cases, it is recommended to review the clinical history for importan