Impact of bleeding events after percutaneous coronary intervention in patients on hemodialysis

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ORIGINAL ARTICLE

Impact of bleeding events after percutaneous coronary intervention in patients on hemodialysis Takahiro Hayashi1 · Koki Shishido1 · Shohei Yokota1 · Hirokazu Miyashita1 · Yuka Mashimo1 · Hiroaki Yokoyama1 · Takashi Nishimoto1 · Noriaki Moriyama1 · Tomoki Ochiai1 · Kazuki Tobita1 · Futoshi Yamanaka1 · Shingo Mizuno1 · Yutaka Tanaka1 · Masato Murakami1 · Saeko Takahashi1 · Shigeru Saito1 Received: 26 December 2019 / Accepted: 3 April 2020 © Springer Japan KK, part of Springer Nature 2020

Abstract Coronary artery disease is common in patients on dialysis; there is a high rate of bleeding events after percutaneous coronary intervention (PCI) in such patients. We investigated the impact of bleeding events after PCI on mortality in patients on hemodialysis. We included 386 consecutive hemodialysis patients who underwent PCI using a drug-eluting stent (DES) between September 2004 and December 2017 in our hospital, and investigated the impact of bleeding events on all-cause mortality after PCI. Bleeding events were assessed by the Thrombolysis in Myocardial Infarction (TIMI) bleeding definition within 24 months after PCI. A total of 42 patients experienced bleeding events. Of these, 30 patients (71.4%) had TIMI major bleeding events and 12 patients (28.6%) had TIMI minor bleeding events. Patients with bleeding events had significantly higher mortality than patients without bleeding events (survival rate, 55.1% vs 81.5%, log-rank: p